Evidence map›Paper›PMID 18987173›Full record

ArticleJournal of clinical microbiology2009

Identification of Candida albicans and Candida glabrata within 1.5 hours directly from positive blood culture bottles with a shortened peptide nucleic acid fluorescence in situ hybridization protocol.

Michael Gherna, William G Merz

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Identification ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  2. Review
  3. Article
  4. Time to positivity of blood culture can predict different Candida species instead of pathogen concentration in candidemia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013
    Article
  5. Invasive fungal infections in patients with cancer in the Intensive Care Unit.International journal of antimicrobial agents · 2012
    Review
  6. Article
  7. Rapid identification of yeasts from positive blood culture bottles by pyrosequencing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2011
    Article
  8. Direct and specific identification of Cryptococcus neoformans in biological samples using fluorescently labelled DNA probes.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2010
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael GhernaDepartment of Pathology, the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
William G Merz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida albicans and Candida glabrata can be identified in blood culture bottles within 2.5 h using peptide nucleic acid fluorescence in situ hybridization. A 1.25-h protocol was compared to the standard with 40 positive (clinical and spiked) blood culture bottles tested in batches of 5. All C. albicans (15) and C. glabrata (16) isolates, alone or mixed, were identified correctly using both protocols, whereas 18 isolates (five other species) were negative by both protocols. This shortened method will significantly reduce the time to identification.

Indexed as

Peptide Nucleic AcidsBloodCandida albicansCandida glabrataHumansIn Situ Hybridization, FluorescenceMycologySensitivity and SpecificityTime FactorsPeptide Nucleic Acids

Identifiers

PMID18987173
PMCPMC2620862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.