Evidence map›Paper›PMID 18987003›Full record

ArticleNucleic acids research2009

Mouse phenome database.

Stephen C Grubb, Terry P Maddatu, Carol J Bult, Molly A Bogue

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.Mammalian genome : official journal of the International Mammalian Genome Society · 2021
    Article
  6. Review
  7. Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory diseases.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  16. Article
  17. Article
  18. Genome-wide association studies in mice.Nature reviews. Genetics · 2012
    Review
  19. Chromosome substitution strains: gene discovery, functional analysis, and systems studies.Mammalian genome : official journal of the International Mammalian Genome Society · 2012
    Review
  20. Association studies in outbred mice in a new era of full-genome sequencing.Mammalian genome : official journal of the International Mammalian Genome Society · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stephen C GrubbThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Terry P Maddatu
Carol J Bult
Molly A Bogue
Jackson Laboratory · US

Funding

MOUSE MODELS OF HEART, LUNG AND BLOOD DISEASEU01HL066611 · NHLBI · JACKSON LABORATORY · PI PETERS, LUANNE L · 2000 to 2007
$25.4M
Shock Center for Aging Research at The Jackson Laborato*P30AG025707 · NIA · JACKSON LABORATORY · PI CHURCHILL, GARY A · 2005 to 2009
$4.1M
Phenome ProjectR01MH071984 · NIMH · JACKSON LABORATORY · PI BOGUE, MOLLY A · 2005 to 2009
$1.6M
The Haplotype Map of the Laboratory Mouse GenomeP41HG003057 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI DALY, MARK J · 2004 to 2005
$1.3M
NHGRI NIH HHS HG003057NHLBI NIH HHS HL66611NIA NIH HHS AG025707NIMH NIH HHS MH071984
6 · The paper itself

Abstract

The Mouse Phenome Database (MPD; http://www.jax.org/phenome) is an open source, web-based repository of phenotypic and genotypic data on commonly used and genetically diverse inbred strains of mice and their derivatives. MPD is also a facility for query, analysis and in silico hypothesis testing. Currently MPD contains about 1400 phenotypic measurements contributed by research teams worldwide, including phenotypes relevant to human health such as cancer susceptibility, aging, obesity, susceptibility to infectious diseases, atherosclerosis, blood disorders and neurosensory disorders. Electronic access to centralized strain data enables investigators to select optimal strains for many systems-based research applications, including physiological studies, drug and toxicology testing, modeling disease processes and complex trait analysis. The ability to select strains for specific research applications by accessing existing phenotype data can bypass the need to (re)characterize strains, precluding major investments of time and resources. This functionality, in turn, accelerates research and leverages existing community resources. Since our last NAR reporting in 2007, MPD has added more community-contributed data covering more phenotypic domains and implemented several new tools and features, including a new interactive Tool Demo available through the MPD homepage (quick link: http://phenome.jax.org/phenome/trytools).

Indexed as

Databases, GeneticGenotypePhenotypeAnimalsGenomicsMiceMice, Inbred StrainsPolymorphism, Single NucleotideQuantitative Trait Loci

Identifiers

PMID18987003
PMCPMC2686531
OpenAlexW4239641275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.