ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2008
A method for improved standardization of in vivo calcaneal time-domain speed-of-sound measurements.
Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Clinical Devices for Bone Assessment.Advances in experimental medicine and biology · 2022Review
- Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020Review
- Monitoring bone changes due to calcium, magnesium, and phosphorus loss in rat femurs using Quantitative Ultrasound.Scientific reports · 2018Article
- Cancellous bone fast and slow waves obtained with Bayesian probability theory correlate with porosity from computed tomography.The Journal of the Acoustical Society of America · 2012Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Although calcaneal speed of sound (SOS) is an effective predictor of osteoporotic fracture risk, clinical SOS measurements exhibit a high degree of inter-system variability. Calcaneal SOS is usually computed from time-of-flight measurements of broadband ultrasound pulses that propagate through the foot. In order to minimize the effects of multi-path interference, many investigators measure time-of-flight from markers near the leading edge of the pulse. The calcaneus is a highly attenuating, highly inhomogeneous bone that distorts propagating ultrasound pulses via frequency-dependent attenuation, reverberation, dispersion, multiple scattering, and refraction. This pulse distortion can produce errors in leading-edge transit-time marker-based SOS measurements. In this paper, an equation to predict dependence of time-domain SOS measurements on system parameters (center frequency and bandwidth), transit-time marker location, and bone properties (attenuation coefficient and thickness) is validated with through-transmission measurements in a bone-mimicking phantom and in 73 women in vivo, using a clinical bone sonometer. In order to test the utility of the formula for suppressing system dependence of SOS measurements, a wideband laboratory data acquisition system was used to make a second set of through-transmission measurements on the phantom. The compensation formula reduced system-dependent leading-edge transit-time marker-based SOS measurements in the phantom from 41 m/s to 5 m/s and reduced average transit-time marker-related SOS variability in 73 women from 40 m/s to 10 m/s. The compensation formula can be used to improve standardization in bone sonometry.
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Registered trials
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