ArticlePediatric surgery international2008
Significance of pulmonary artery size and blood flow as a predictor of outcome in congenital diaphragmatic hernia.
Article in Pediatric surgery international, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Pulmonary artery diameter ratio as a prognostic indicator of congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Article
- Early echocardiographic pulmonary artery measurements as prognostic indicators in left congenital diaphragmatic hernia.BMC pediatrics · 2023Article
- Assessment of pulmonary artery size at birth as a prognostic factor in congenital diaphragmatic hernia: results of a multicenter study in Japan.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Quantitative cardiopulmonary magnetic resonance imaging in neonatal congenital diaphragmatic hernia.Pediatric radiology · 2022Article
- Evaluation and Monitoring of Pulmonary Hypertension in Neonates With Congenital Diaphragmatic Hernia.Current treatment options in cardiovascular medicine · 2019Review
- Safety of surgery for neonatal congenital diaphragmatic hernia as reflected by arterial blood gas monitoring: thoracoscopic versus open repair.Pediatric surgery international · 2015Article
- Surgical intervention for congenital diaphragmatic hernia: open versus thoracoscopic surgery.Pediatric surgery international · 2013Article
- A review of congenital diaphragmatic hernia.Australasian journal of ultrasound in medicine · 2013Review
- Pulmonary artery size as an indication for thoracoscopic repair of congenital diaphragmatic hernia in neonates.Pediatric surgery international · 2012Article
- Pulmonary artery size has prognostic value in low birth weight infants with congenital diaphragmatic hernia.Pediatric surgery international · 2011Article
- Echocardiographic measures of ventricular function and pulmonary artery size: prognostic markers of congenital diaphragmatic hernia?Journal of perinatology : official journal of the California Perinatal Association · 2011Article
- Indications for thoracoscopic repair of congenital diaphragmatic hernia in neonates.Pediatric surgery international · 2011Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine if pulmonary artery size and blood flow have prognostic value in congenital diaphragmatic hernia (CDH).
methodsTwenty-eight consecutive left-sided CDH patients treated according to a standard protocol with high frequency oscillatory ventilation (HFOV) + nitric oxide (NO) had right and left pulmonary artery (RPA, LPA) diameters, LPA/RPA diameter (L/R) ratios, and PA blood flows examined by echocardiography (EC) on days 0, 2, and 5 after birth and compared prospectively.
resultsTwenty-two patients (78.6%) survived. Of these, 15 required NO (NO-s), and seven did not (non-NO-s). All six patients that died required NO (NO-d). RPA in the NO-d group was significantly smaller than in the NO-s or non-NO-s groups on day 0 (2.90 +/- 0.41 vs. 3.40 +/- 0.49 or 4.01 +/- 0.43; P < 0.01, respectively). LPA in the NO-d group was significantly smaller than in the non-NO-s on day 0 (2.13 +/- 0.45 vs. 3.39 +/- 0.34; P < 0.01). L/R ratios in NO subjects were significantly smaller (NO-s 0.74 +/- 0.11; NO-d 0.73 +/- 0.11) than in non-NO-s subjects (0.84 +/- 0.03) on day 0 (P < 0.01). PA diameters and L/R ratios did not change significantly from day 0 to day 5 in all three groups. There was LPA flow on day 0 in all non-NO-s subjects, but none in all NO subjects. In the NO-s group, LPA flow was confirmed in 87% (13/15) on day 2 and in 100% on day 5, however, there was no LPA flow from day 0 to day 5 in any of the NO-d group.
conclusionOur data indicate that PA diameters on day 0 and LPA flow are strongly prognostic in left-sided CDH and L/R ratio would appear to be a simple highly reliable indicator of the necessity for NO therapy.
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