Evidence map›Paper›PMID 18983934›Full record

ReviewCurrent opinion in microbiology2008

How a cyanobacterium tells time.

Guogang Dong, Susan S Golden

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 114 citations in OpenAlex.

  1. Ecosystem relocation on Snowball Earth: Polar-alpine ancestry of the extant surface biosphere?Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Snowball Earth, population bottleneck andProceedings. Biological sciences · 2021
    Article
  5. Review
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  7. Review
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  15. Different iron sources to study the physiology and biochemistry of iron metabolism in marine micro-algae.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2014
    Article
  16. Article
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  19. Ultradian metabolic rhythm in the diazotrophic cyanobacterium Cyanothece sp. ATCC 51142.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  20. Small molecule modifiers of circadian clocks.Cellular and molecular life sciences : CMLS · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Guogang DongCenter for Biological Clocks Research and Department of Biology, Texas A&M University, College Station, TX 77843-3258, United States.
Susan S Golden
Texas A&M University · US

Funding

The Circadian Clock in the Context of the Cyanobacterial CellP01NS039546 · NINDS · TEXAS A&M UNIVERSITY SYSTEM · PI THOMAS, TERRY L · 2000 to 2010
$10.6M
THE PATHWAY THAT SETS THE CYANOBACTERIAL CIRCADIAN CLOCKR01GM062419 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDEN, SUSAN S · 2001 to 2015
$3.9M
NIGMS NIH HHS R01 GM062419NIGMS NIH HHS R01 GM62419NINDS NIH HHS P01 NS039546NINDS NIH HHS P01 NS39546
6 · The paper itself

Abstract

The cyanobacterium Synechococcus elongatus builds a circadian clock on an oscillator composed of three proteins, KaiA, KaiB, and KaiC, which can recapitulate a circadian rhythm of KaiC phosphorylation in vitro. The molecular structures of all three proteins are known, and the phosphorylation steps of KaiC, the interaction dynamics among the three Kai proteins, and a weak ATPase activity of KaiC have all been characterized. An input pathway of redox-sensitive proteins uses photosynthetic function to relay light/dark information to the oscillator, and signal transduction proteins of well-known families broadcast temporal information to the genome, where global changes in transcription and a compaction of the chromosome are clock regulated.

Indexed as

Circadian RhythmBacterial ProteinsCircadian Rhythm Signaling Peptides and ProteinsDarknessGene Expression Regulation, BacterialLightSynechococcusBacterial ProteinsCircadian Rhythm Signaling Peptides and ProteinsKaiA protein, cyanobacteriaKaiB protein, cyanobacteriaKaiC protein, cyanobacteria

Identifiers

PMID18983934
PMCPMC2692899
OpenAlexW2093122082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.