Evidence map›Paper›PMID 18983701›Full record

ReviewJournal of biology2008

X-chromosome inactivation: the molecular basis of silencing.

Barbara Panning

Open access · goldAbstract readReview
In one paragraph

Review in Journal of biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 60 citations in OpenAlex.

  1. Sex differences in brain glucose metabolism and Alzheimer's disease risk and progression.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  13. X Chromosome Factor Kdm6a Enhances Cognition Independent of Its Demethylase Function in the Aging XY Male Brain.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Barbara PanningDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA. bpanning@biochem.ucsf.edu
University of California, San Francisco · US

Funding

Xist RNA and Regulation of Chromatin StructureR01GM063671 · NIGMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI PANNING, BARBARA · 2001 to 2005
$1.2M
NIGMS NIH HHS R01 GM063671
6 · The paper itself

Abstract

X-chromosome inactivation occurs randomly for one of the two X chromosomes in female cells during development. Inactivation occurs when RNA transcribed from the Xist gene on the X chromosome from which it is expressed spreads to coat the whole X chromosome. In the first issue of Epigenetics and Chromatin, Nesterova and colleagues investigate the role of the RNA interference pathway enzyme Dicer in DNA methylation of the Xist promoter.

Indexed as

Genes, X-LinkedAnimalsDEAD-box RNA HelicasesEmbryo, MammalianEmbryonic Stem CellsEndoribonucleasesFemaleGene SilencingMaleMiceMutationRibonuclease IIIRNA InterferenceX Chromosome InactivationDEAD-box RNA HelicasesDicer1 protein, mouseEndoribonucleasesRibonuclease III

Identifiers

PMID18983701
PMCPMC2776401
OpenAlexW2118197059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.