ReviewClinical interventions in aging2008
Mild cognitive impairment: conceptual, assessment, ethical, and social issues.
Review in Clinical interventions in aging, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Dose-Response Meta-Analysis on Tooth Loss With the Risk of Cognitive Impairment and Dementia.Journal of the American Medical Directors Association · 2021Pooled it
- Investigating Auditory Electrophysiological Measures of Participants with Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review and Meta-Analysis of Event-Related Potential Studies.Journal of Alzheimer's disease : JAD · 2021Pooled it
- Living With Ambiguity: A Metasynthesis of Qualitative Research on Mild Cognitive Impairment.The Gerontologist · 2015Pooled it
- Barriers to and facilitators of comprehensive geriatric assessment in primary care in France: a qualitative study exploring physicians' and nurses' experiences.BMC primary care · 2025Trial
- TECH preserves global cognition of older adults with MCI compared with a control group: a randomized controlled trial.Aging clinical and experimental research · 2024Trial
- A novel technology to screen for cognitive impairment in the elderly.American journal of Alzheimer's disease and other dementias · 2011Trial
- Clinical practice guidelines for assessment and management of mild neurocognitive disorder.Indian journal of psychiatry · 2025Article
- The effects of herbal medicine (Jujadokseo-hwan) on quality of life in patients with mild cognitive impairment: Cost-effectiveness analysis alongside randomized controlled trial.Integrative medicine research · 2023Article
- Prediction of Progression from Mild Cognitive Impairment to Alzheimer's disease with Longitudinal and Multimodal Data.Frontiers in dementia · 2023Article
- Detecting Cognitive Impairment Status Using Keystroke Patterns and Physical Activity Data among the Older Adults: A Machine Learning Approach.Journal of healthcare engineering · 2021Article
- Mild cognitive impairment: narrative review of taxonomies and systematic review of their prediction of incident Alzheimer's disease dementia.BJPsych bulletin · 2020Article
- Health Outcome Prioritization in Alzheimer's Disease: Understanding the Ethical Landscape.Journal of Alzheimer's disease : JAD · 2020Review
- Prediction of future cognitive impairment among the community elderly: A machine-learning based approach.Scientific reports · 2019Article
- Stakeholders' Views on Early Diagnosis for Alzheimer's Disease, Clinical Trial Participation and Amyloid PET Disclosure: A Focus Group Study.Journal of bioethical inquiry · 2019Article
- Review of the Ethical Issues of a Biomarker-Based Diagnoses in the Early Stage of Alzheimer's Disease.Journal of bioethical inquiry · 2018Review
- Analysis of the Retinal Nerve Fiber Layer Thickness in Alzheimer Disease and Mild Cognitive Impairment.Korean journal of ophthalmology : KJO · 2017Article
- Macular Thickness in Subjective Memory Complaints and Mild Cognitive Impairment: A Non-Invasive Biomarker.Neuro-ophthalmology (Aeolus Press) · 2016Article
- Thinner changes of the retinal nerve fiber layer in patients with mild cognitive impairment and Alzheimer's disease.BMC neurology · 2015Article
- Retinal alterations in mild cognitive impairment and Alzheimer's disease: an optical coherence tomography study.Journal of neurology · 2014Article
- Help-seeking preferences in the area of mild cognitive impairment: comparing family physicians and the lay public.Clinical interventions in aging · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mild cognitive impairment (MCI) is defined as a condition characterized by newly acquired cognitive decline to an extent that is beyond that expected for age or educational background, yet not causing significant functional impairment. The concept of MCI has received considerable attention in the literature over the past few years, and aspects related to its definition, prevalence, and evolution have been extensively studied and reviewed. Here we attempt to synthesize the implications of the current status of this entity, focusing on the conceptual, methodological, and, in particular, the social and ethical aspects of MCI which have attracted less attention. We discuss the weaknesses of the concept of MCI, which is heterogeneous in etiology, manifestations, and outcomes, and suggest that the emergence of the syndrome at this stage reflects industrial interests related to possible development of drugs for this disorder. On the other hand, the formal diagnosis of MCI, with its implications that the person may develop dementia, may have a grave impact on the psychological state of the individual, at a stage when prediction of outcome is tenuous and possibilities of useful interventions are meager. We present suggestions for the direction of future research in these areas.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.