ArticleIntensive care medicine2009
Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study.
Article in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01301352 (The Efficacy and Safety of Gastric Feeding in Critically Ill Pediatric Patients Receiving Non-invasive Positive Pressure Ventilation), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Efficacy and Safety of Gastric Feeding in Critically Ill Pediatric Patients Receiving Non-invasive Positive Pressure Ventilation: A Pilot Study
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 167 citations in OpenAlex.
- Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC).Intensive care medicine · 2017Guideline
- The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2011Guideline
- Noninvasive ventilation in pediatric acute respiratory failure by means of a conventional volumetric ventilator.World journal of pediatrics : WJP · 2010Trial
- Risk factors and outcomes of pediatric non-invasive respiratory support failure in Latin America.Journal of intensive medicine · 2025Article
- Implications of sedation during the use of noninvasive ventilation in children with acute respiratory failure (SEDANIV Study).Critical care (London, England) · 2024Observational
- A Review of Prolonged Mechanical Ventilation in Pediatric Cardiac Surgery Patients: Risk Factors and Implications.Journal of multidisciplinary healthcare · 2024Review
- Predictors of Non-invasive Ventilation Failure and Associated Factors Among the COVID-19 Patients Admitted to Intensive Care Unit.Anesthesiology and pain medicine · 2023Article
- Predictors of Failure of Noninvasive Ventilation in Critically Ill Children.Journal of pediatric intensive care · 2023Article
- Clinical Profile and Outcome of Children Requiring Noninvasive Ventilation (NIV).Indian journal of pediatrics · 2022Observational
- Weaning from ventilation and extubation of children in critical care.BJA education · 2022Review
- Reduced Air Leakage During Non-Invasive Ventilation Using a Simple Anesthetic Mask With 3D-Printed Adaptor in an Anthropometric Based Pediatric Head-Lung Model.Frontiers in pediatrics · 2022Article
- Feasibility of Pediatric Non-Invasive Respiratory Support in Low- and Middle-Income Countries.Indian pediatrics · 2021Review
- Risk Factors Associated with Mechanical Ventilation in Critical Bronchiolitis.Children (Basel, Switzerland) · 2021Article
- SpOScientific reports · 2021Article
- A multicentered study on efficiency of noninvasive ventilation procedures (SAFE-NIV)Turkish journal of medical sciences · 2021Observational
- Predictive factors of continuous negative extrathoracic pressure management failure in children with moderate to severe respiratory syncytial virus infection.Scientific reports · 2021Article
- Risk Factors for Noninvasive Ventilation Failure in Children Post-Hematopoietic Cell Transplant.Frontiers in oncology · 2021Article
- Non-invasive Ventilation for Pediatric Hypoxic Acute Respiratory Failure Using a Simple Anesthetic Mask With 3D Printed Adaptor: A Case Report.Frontiers in pediatrics · 2021Article
- [Predictive factors for failure of continuous positive airway pressure treatment in infants with bronchiolitis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Clinical characteristics and outcomes associated with nasal intermittent mandatory ventilation in acute pediatric respiratory failure.World journal of critical care medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIdentification of predictive factors for non-invasive ventilation (NIV) failure and determination of NIV characteristics.
designProspective observational study.
settingPaediatric Intensive Care Unit in a University Hospital. PATIENTS AND MEASUREMENTS: A total of 116 episodes were included. Clinical data collected were respiratory rate (RR), heart rate and FiO(2) before NIV began. Same data and expiratory and support pressures were collected at 1, 6, 12, 24 and 48 h. Conditions precipitating acute respiratory failure (ARF) were classified into two groups: type 1 (38 episodes) and type 2 (78 episodes). Ventilation-perfusion impairment was the main respiratory failure mechanism in type 1, and hypoventilation in type 2. Factors predicting NIV failure were determined by multivariate analysis.
resultsMost common admission diagnoses were pneumonia (81.6%) in type 1 and bronchiolitis (39.7%) and asthma (42.3%) in type 2. Complications secondary to NIV were detected in 23 episodes (20.2%). NIV success rate was 84.5% (68.4% in type 1 and 92.3% in type 2). Type 1 patients showed a higher risk of NIV failure compared to type 2 (OR 11.108; CI 95%, 2.578-47.863). A higher PRISM score (OR 1.138; CI 95%, 1.022-1.267), and a lower RR decrease at 1 h and at 6 h (OR 0.926; CI 95%, 0.860-0.997 and OR 0.911; CI 95%, 0.837-0.991, respectively) were also independently associated with NIV failure.
conclusionsNIV is a useful respiratory support technique in paediatric patients. Type 1 group classification, higher PRISM score, and lower RR decrease during NIV were independent risk factors for NIV failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.