Evidence map›Paper›PMID 18980370›Full record

ReviewBioconjugate chemistry2008

DNA-mediated electrochemistry.

Alon A Gorodetsky, Marisa C Buzzeo, Jacqueline K Barton

Abstract readReview
In one paragraph

Review in Bioconjugate chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Using DNA devices to track anticancer drug activity.Biosensors & bioelectronics · 2016
    Article
  15. Nanostructured gold dsDNA sensor for early detection of breast cancer by beta protein 1 (BPJournal of electroanalytical chemistry (Lausanne, Switzerland) · 2015
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alon A GorodetskyDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.
Marisa C Buzzeo
Jacqueline K Barton

Funding

ELECTROCHEMICAL DNA-BASED SENSORSR01GM061077 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BARTON, JACQUELINE K · 2000 to 2017
$5.2M
NIGMS NIH HHS GM61077NIGMS NIH HHS R01 GM061077
6 · The paper itself

Abstract

The base pair stack of DNA has been demonstrated as a medium for long-range charge transport chemistry both in solution and at DNA-modified surfaces. This chemistry is exquisitely sensitive to structural perturbations in the base pair stack as occur with lesions, single base mismatches, and protein binding. We have exploited this sensitivity for the development of reliable electrochemical assays based on DNA charge transport at self-assembled DNA monolayers. Here, we discuss the characteristic features, applications, and advantages of DNA-mediated electrochemistry.

Indexed as

AnimalsDNAElectrochemistryLigandsNucleic Acid HybridizationProtein BindingProteinsDNALigandsProteins

Identifiers

PMID18980370
PMCPMC2663395

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.