ArticleJournal of bacteriology2009
RpoH(II) activates oxidative-stress defense systems and is controlled by RpoE in the singlet oxygen-dependent response in Rhodobacter sphaeroides.
Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 81 citations in OpenAlex.
- The Impact of the Major Endoribonucleases RNase E and RNase III and of the sRNA StsR on Photosynthesis Gene Expression inInternational journal of molecular sciences · 2024Article
- Polyhydroxyalkanoate involvement in stress-survival of two psychrophilic bacterial strains from the High Arctic.Applied microbiology and biotechnology · 2024Article
- Function of the RNA-targeting class 2 type VI CRISPR Cas system ofFrontiers in microbiology · 2024Article
- The Regulatory Functions of the Multiple Alternative Sigma Factors RpoE, RpoHI, and RpoHII Depend on the Growth Phase inMicroorganisms · 2023Article
- Ribonuclease E strongly impacts bacterial adaptation to different growth conditions.RNA biology · 2023Article
- A Small RNA, UdsC, Interacts with the RInternational journal of molecular sciences · 2022Article
- Gram-Negative Bacterial Envelope Homeostasis under Oxidative and Nitrosative Stress.Microorganisms · 2022Review
- β-Lactam Resistance inJournal of bacteriology · 2022Article
- Promoter Architecture Differences amongmSystems · 2021Article
- A Complex Network of Sigma Factors and sRNA StsR Regulates Stress Responses inInternational journal of molecular sciences · 2021Article
- sRNA-mediated RNA processing regulates bacterial cell division.Nucleic acids research · 2021Article
- The small DUF1127 protein CcaF1 from Rhodobacter sphaeroides is an RNA-binding protein involved in sRNA maturation and RNA turnover.Nucleic acids research · 2021Article
- Oxidative Stress in Bacteria and the Central Dogma of Molecular Biology.Frontiers in molecular biosciences · 2021Review
- Adaptation to Photooxidative Stress: Common and Special Strategies of the AlphaproteobacteriaMicroorganisms · 2020Article
- Shedding light on a Group IV (ECF11) alternative σ factor.Molecular microbiology · 2019Review
- Catalase Expression in Azospirillum brasilense Sp7 Is Regulated by a Network Consisting of OxyR and Two RpoH Paralogs and Including an RpoE1→RpoH5 Regulatory Cascade.Applied and environmental microbiology · 2018Article
- Transcriptome analysis reveals the molecular mechanisms of the defense response to gray leaf spot disease in maize.BMC genomics · 2018Article
- RNase E cleavage shapes the transcriptome ofLife science alliance · 2018Article
- The PhyR homolog RSP_1274 of Rhodobacter sphaeroides is involved in defense of membrane stress and has a moderate effect on RpoE (RSP_1092) activity.BMC microbiology · 2018Article
- Identification and Characterization of aFrontiers in microbiology · 2018Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photosynthetic organisms need defense systems against photooxidative stress caused by the generation of highly reactive singlet oxygen ((1)O(2)). Here we show that the alternative sigma factor RpoH(II) is required for the expression of important defense factors and that deletion of rpoH(II) leads to increased sensitivity against exposure to (1)O(2) and methylglyoxal in Rhodobacter sphaeroides. The gene encoding RpoH(II) is controlled by RpoE, and thereby a sigma factor cascade is constituted. We provide the first in vivo study that identifies genes controlled by an RpoH(II)-type sigma factor, which is widely distributed in the Alphaproteobacteria. RpoH(II)-dependent genes encode oxidative-stress defense systems, including proteins for the degradation of methylglyoxal, detoxification of peroxides, (1)O(2) scavenging, and redox and iron homeostasis. Our experiments indicate that glutathione (GSH)-dependent mechanisms are involved in the defense against photooxidative stress in photosynthetic bacteria. Therefore, we conclude that systems pivotal for the organism's defense against photooxidative stress are strongly dependent on GSH and are specifically recognized by RpoH(II) in R. sphaeroides.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.