Evidence map›Paper›PMID 18978021›Full record

ArticleNucleic acids research2009

ERGR: An ethanol-related gene resource.

An-Yuan Guo, Bradley T Webb, Michael F Miles, Mark P Zimmerman, Kenneth S Kendler, Zhongming Zhao

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Genetics and genomics of alcohol sensitivity.Molecular genetics and genomics : MGG · 2014
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2012
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

An-Yuan GuoDepartment of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA.
Bradley T Webb
Michael F Miles
Mark P Zimmerman
Kenneth S Kendler
Zhongming Zhao
Virginia Commonwealth University · US

Funding

IRISH AFFECTED SIB PAIR STUDY OF ALCOHOL DEPENDENCER01AA011408 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN · 1997 to 2005
$3.4M
INIA-STRESS: Informatics and Analysis CoreU01AA016662 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI WILLIAMS, ROBERT W. · 2007 to 2016
$2.9M
Of Mice and Primates: Gene Networks in Excessive Ethanol Consumption and AnxietyU01AA016667 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILES, MICHAEL F · 2007 to 2016
$2.4M
Project 3: Cross Species Characterization of Gene Networks in Acute ResponsesP20AA017828 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN, MILES, MICHAEL F · 2009 to 2012
$2.2M
Functional genomics of ethanol craving and naltrexoneR01AA014717 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILES, MICHAEL F · 2004 to 2008
$1.6M
Microarray Analysis of Acute Ethanol Effects in BrainR01AA013678 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILES, MICHAEL F. · 2001 to 2003
$1.1M
Generation of Ethanol Response Gene Resource by Large-Scale Data IntegrationR21AA017437 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI ZHAO, ZHONGMING · 2008 to 2009
$398k
NIAAA NIH HHS P20 AA017828NIAAA NIH HHS R01AA011408NIAAA NIH HHS R01 AA013678NIAAA NIH HHS R01AA014717NIAAA NIH HHS R21 AA017437NIAAA NIH HHS R21AA017437NIAAA NIH HHS U01 AA016662NIAAA NIH HHS U01AA016662NIAAA NIH HHS U01 AA016667NIAAA NIH HHS U01AA016667
6 · The paper itself

Abstract

Over the last decade rapid progress has been made in the study of ethanol-related traits including alcohol abuse and dependence, and behavioral responses to ethanol in both humans and animal models. To collect, curate, integrate these results so as to make them easily accessible and interpretable for researchers, we developed ERGR, a comprehensive ethanol-related gene resource. We collected and curated more than 30 large-scale data sets including linkage, association and microarray gene expression from the literature and 21 mouse QTLs from public databases. At present, the ERGR deposits ethanol-related information of approximately 7000 genes from five organisms: human (3311), mouse (2129), rat (679), fly (614) and worm (228). ERGR provides gene annotations and orthologs, detailed gene study information (e.g. fold changes of gene expression, P-values), and both the text and BLAST searches. Moreover, ERGR has data integration tools such as for data union and intersection, and candidate gene selection based on evidence in multiple datasets or organisms. The ERGR database is evolving with new data releases. More functions will also be added. ERGR has a user-friendly web interface with browse and search functions at multiple levels. It is freely available at http://bioinfo.vipbg.vcu.edu/ERGR/.

Indexed as

Databases, GeneticAlcoholismAnimalsEthanolGene ExpressionHumansMiceQuantitative Trait LociRatsSystems IntegrationUser-Computer InterfaceEthanol

Identifiers

PMID18978021
PMCPMC2686553
OpenAlexW2066617812

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.