ArticleEmerging infectious diseases2008
Successful treatment of disseminated Acanthamoeba sp. infection with miltefosine.
Article in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 119 citations in OpenAlex.
- Identification of Potent and Selective Inhibitors ofJournal of medicinal chemistry · 2024Article
- DisseminatedFrontiers in medicine · 2024Article
- The role of apoptosis and oxidative stress in the pathophysiology of Acanthamoeba spp. infection in the kidneys of hosts with different immunological status.Parasites & vectors · 2023Article
- Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations.Antibiotics (Basel, Switzerland) · 2023Article
- Pathogenic free-living amoebic encephalitis from 48 cases in China: A systematic review.Frontiers in neurology · 2023Review
- Successful Treatment of Primary Amoebic Meningoencephalitis Using a Novel Therapeutic Regimen Including Miltefosine and Voriconazole.Acta parasitologica · 2022Article
- Opportunistic free-living amoebal pathogens.Pathogens and global health · 2022Article
- Clinical Improvement of Disseminated Acanthamoeba Infection in a Patient with Advanced HIV Using a Non-Miltefosine-Based Treatment Regimen in a Low-Resource Setting.Tropical medicine and infectious disease · 2022Article
- Acanthamoeba castellanii encephalitis in a patient with AIDS: a case report and literature review.The Lancet. Infectious diseases · 2022Review
- A functional genomic screen in Saccharomyces cerevisiae reveals divergent mechanisms of resistance to different alkylphosphocholine chemotherapeutic agents.G3 (Bethesda, Md.) · 2021Article
- Review
- Immunopathogenicity ofInternational journal of molecular sciences · 2021Review
- The Effect of Anti-Amoebic Agents and Ce6-PDT onTranslational vision science & technology · 2020Article
- In vitro activity of Camellia sinensis (green tea) against trophozoites and cysts of Acanthamoeba castellanii.International journal for parasitology. Drugs and drug resistance · 2020Article
- A Surviving Case of Acanthamoeba Granulomatous Amebic Encephalitis in a Hematopoietic Stem Cell Transplant Recipient.The American journal of case reports · 2020Article
- Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box onPathogens (Basel, Switzerland) · 2020Article
- Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases.Journal of family medicine and primary care · 2020Article
- Identification of plicamycin, TG02, panobinostat, lestaurtinib, and GDC-0084 as promising compounds for the treatment of central nervous system infections caused by the free-living amebae Naegleria, Acanthamoeba and Balamuthia.International journal for parasitology. Drugs and drug resistance · 2019Article
- Acanthamoeba in Southeast Asia - Overview and Challenges.The Korean journal of parasitology · 2019Review
- Cellulose fibrils formation and organisation of cytoskeleton during encystment are essential for Acanthamoeba cyst wall architecture.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.