ArticleExperimental brain research2009
The effect of test TMS intensity on short-interval intracortical inhibition in different excitability states.
Article in Experimental brain research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Central Post-Stroke Pain: An Integrative Review of Somatotopic Damage, Clinical Symptoms, and Neurophysiological Measures.Frontiers in neurology · 2021Pooled it
- Cerebellar transcranial alternating current stimulation in the gamma range applied during the acquisition of a novel motor skill.Scientific reports · 2020Trial
- The aging motor system as a model for plastic changes of GABA-mediated intracortical inhibition and their behavioral relevance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- The effects of whole-body vibration on the cross-transfer of strength.TheScientificWorldJournal · 2012Trial
- Versatility of Transcranial Magnetic Stimulation: A Review of Diagnostic and Therapeutic Applications.Brain sciences · 2026Review
- Modulation of primary motor cortex after experimentally induced and use-dependent plasticity in young and older adults.Experimental brain research · 2025Article
- Lesion location changes the association between brain excitability and the performance of a short-term visuomotor adaptation task post-stroke.Brain communications · 2025Article
- Disruptive compensatory mechanisms in fibromyalgia syndrome and their association with pharmacological agents.Experimental brain research · 2024Article
- Physiological Biomarkers of Upper Motor Neuron Dysfunction in ALS.Brain sciences · 2024Review
- When the heart inhibits the brain: Cardiac phases modulate short-interval intracortical inhibition.iScience · 2024Article
- Motor potentials evoked by transcranial magnetic stimulation: interpreting a simple measure of a complex system.The Journal of physiology · 2023Review
- Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Review
- Reliability of corticospinal excitability and intracortical inhibition in biceps femoris during different contraction modes.The European journal of neuroscience · 2023Article
- Considerable effects of lateralization and aging in intracortical excitation and inhibition.Frontiers in neuroscience · 2023Article
- Anodal-TDCS over Left-DLPFC Modulates Motor Cortex Excitability in Chronic Lower Back Pain.Brain sciences · 2022Article
- The recruitment of indirect waves within primary motor cortex during motor imagery: A directional transcranial magnetic stimulation study.The European journal of neuroscience · 2022Article
- Motor cortex excitability in chronic low back pain.Experimental brain research · 2022Article
- Inhibitory and excitatory responses in the dorso-medial prefrontal cortex during threat processing.Frontiers in neuroscience · 2022Article
- Associations between Task-Related Modulation of Motor-Evoked Potentials and EEG Event-Related Desynchronization in Children with ADHD.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Primary motor cortex function and motor skill acquisition: insights from threshold-hunting TMS.Experimental brain research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The paired-pulse transcranial magnetic stimulation (TMS) paradigm is increasingly employed to examine intracortical inhibitory processes in different motor tasks. Short-interval intracortical inhibition (SICI) has been shown to vary with the size of the MEP elicited by the test TMS pulse. This suggests that factors that alter MEP size, such as changes in cortical excitability, may confound the interpretation of SICI. However, the effect of excitability on SICI has not been systematically investigated. The present study examined SICI in 11 volunteers. The effect of test TMS intensities ranging from 90 to 150% resting motor threshold (RMT) on SICI was examined in three excitability states in the right first dorsal interosseous muscle: rest, isometric abduction of the left index finger (Contra) and isometric abduction of the right index finger (Active). For all excitability states SICI was not observed when test TMS intensity was less than 110% resting motor threshold. This was true even for the Active condition in which 90 and 100% test TMS intensities elicited large and consistent MEPs. For all conditions moderately suprathreshold test TMS intensities (110-120% RMT) yielded the greatest measure of SICI; increasing test TMS intensities resulted in a progressive reduction in the estimate of SICI. These results suggest that estimates of SICI are systematically affected by the intensity of the test TMS pulse, regardless of excitability state. The results suggest that SICI should be examined using a constant test TMS intensity regardless of changes in cortical excitability and test MEP size.
Indexed as
Identifiers
18974984What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.