ArticleNucleic acids research2009
SysZNF: the C2H2 zinc finger gene database.
Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- TSProm: deep learning framework to predict tissue-specific regulatory logic.NAR genomics and bioinformatics · 2026Article
- TSProm: Deciphering the Genomic Context of Tissue Specificity.bioRxiv : the preprint server for biology · 2025Article
- Novel Compound Heterozygous Variants in ZNF526 Causing Dentici-Novelli Neurodevelopmental Syndrome: A Case Report and Literature Review.Molecular genetics & genomic medicine · 2025Review
- Genome-Wide Analysis of Q-Type C2H2 ZFP Genes in Response to Biotic and Abiotic Stresses in Sugar Beet.Biology · 2023Article
- Analysis of the C2H2 Gene Family in Maize (Life (Basel, Switzerland) · 2022Article
- ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin.Nature communications · 2017Article
- Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding.Genome biology · 2017Article
- Mammalian Comparative Genomics Reveals Genetic and Epigenetic Features Associated with Genome Reshuffling in Rodentia.Genome biology and evolution · 2016Article
- Deep vertebrate roots for mammalian zinc finger transcription factor subfamilies.Genome biology and evolution · 2014Article
- Exome sequencing identifies three novel candidate genes implicated in intellectual disability.PloS one · 2014Article
- Article
- DNA recognition of 5-carboxylcytosine by a Zfp57 mutant at an atomic resolution of 0.97 Å.Biochemistry · 2013Article
- A study on the distribution of 37 well conserved families of C2H2 zinc finger genes in eukaryotes.BMC genomics · 2013Article
- A common mode of recognition for methylated CpG.Trends in biochemical sciences · 2013Review
- A new family of predicted Krüppel-like factor genes and pseudogenes in placental mammals.PloS one · 2013Article
- Global and stage specific patterns of Krüppel-associated-box zinc finger protein gene expression in murine early embryonic cells.PloS one · 2013Article
- Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs.Genome research · 2011Article
- A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.BMC genomics · 2011Article
- A novel KRAB domain-containing zinc finger transcription factor ZNF431 directly represses Patched1 transcription.The Journal of biological chemistry · 2011Article
- Re-programming DNA-binding specificity in zinc finger proteins for targeting unique address in a genome.Systems and synthetic biology · 2010Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
C2H2 zinc finger (C2H2-ZNF) genes are one of the largest and most complex gene super-families in metazoan genomes, with hundreds of members in the human and mouse genome. The ongoing investigation of this huge gene family requires computational support to catalog genotype phenotype comparisons of C2H2-ZNF genes between related species and finally to extend the worldwide knowledge on the evolution of C2H2-ZNF genes in general. Here, we systematically collected all the C2H2-ZNF genes in the human and mouse genome and constructed a database named SysZNF to deposit available datasets related to these genes. In the database, each C2H2-ZNF gene entry consists of physical location, gene model (including different transcript forms), Affymetrix gene expression probes, protein domain structures, homologs (and synteny between human and mouse), PubMed references as well as links to relevant public databases. The clustered organization of the C2H2-ZNF genes is highlighted. The database can be searched using text strings or sequence information. The data are also available for batch download from the web site. Moreover, the graphical gene model/protein view system, sequence retrieval system and some other tools embedded in SysZNF facilitate the research on the C2H2 type ZNF genes under an integrative view. The database can be accessed from the URL http://epgd.biosino.org/SysZNF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.