ArticleNucleic acids research2009
TcSNP: a database of genetic variation in Trypanosoma cruzi.
Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Main Cardiac Histopathologic Alterations in the Acute Phase ofPathogens (Basel, Switzerland) · 2023Article
- Genomic surveillance: a potential shortcut for effective Chagas disease management.Memorias do Instituto Oswaldo Cruz · 2023Article
- Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease.PLoS pathogens · 2021Article
- Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants.Molecular & cellular proteomics : MCP · 2015Article
- Genetic profiling of the isoprenoid and sterol biosynthesis pathway genes of Trypanosoma cruzi.PloS one · 2014Article
- A genomic scale map of genetic diversity in Trypanosoma cruzi.BMC genomics · 2012Article
- Diagnostic peptide discovery: prioritization of pathogen diagnostic markers using multiple features.PloS one · 2012Article
- A semantic problem solving environment for integrative parasite research: identification of intervention targets for Trypanosoma cruzi.PLoS neglected tropical diseases · 2012Article
- A simple strain typing assay for Trypanosoma cruzi: discrimination of major evolutionary lineages from a single amplification product.PLoS neglected tropical diseases · 2012Article
- Pathogenesis of chagas' disease: parasite persistence and autoimmunity.Clinical microbiology reviews · 2011Review
- Nucleic Acids Research annual Database Issue and the NAR online Molecular Biology Database Collection in 2009.Nucleic acids research · 2009Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The TcSNP database (http://snps.tcruzi.org) integrates information on genetic variation (polymorphisms and mutations) for different stocks, strains and isolates of Trypanosoma cruzi, the causative agent of Chagas disease. The database incorporates sequences (genes from the T. cruzi reference genome, mRNAs, ESTs and genomic sequences); multiple sequence alignments obtained from these sequences; and single-nucleotide polymorphisms and small indels identified by scanning these multiple sequence alignments. Information in TcSNP can be readily interrogated to arrive at gene sets, or SNP sets of interest based on a number of attributes. Sequence similarity searches using BLAST are also supported. This first release of TcSNP contains nearly 170,000 high-confidence candidate SNPs, derived from the analysis of annotated coding sequences. As new sequence data become available, TcSNP will incorporate these data, mapping new candidate SNPs onto the reference genome sequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.