Evidence map›Paper›PMID 18971360›Full record

ArticleJournal of clinical microbiology2009

Ciprofloxacin-resistant Salmonella enterica serovar typhi from Kuwait with novel mutations in gyrA and parC genes.

Tzonyo Dimitrov, Ali A Dashti, Ossama Albaksami, Edet E Udo, Mehrez M Jadaon, M John Albert

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever).The Cochrane database of systematic reviews · 2011
    Pooled it
  2. Article
  3. Review
  4. The Evolution of Fluoroquinolone Resistance inInternational journal of molecular sciences · 2021
    Article
  5. Article
  6. Draft Genome Sequence ofGenome announcements · 2017
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Contribution of different mechanisms to the resistance to fluoroquinolones in clinical isolates of Salmonella enterica.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tzonyo DimitrovDepartment of Microbiology, Faculty of Medicine, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.
Ali A Dashti
Ossama Albaksami
Edet E Udo
Mehrez M Jadaon
M John Albert

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood isolates of Salmonella enterica serovar Typhi from two recently returned Bangladeshi patients in Kuwait were ciprofloxacin resistant, with ciprofloxacin MICs of 12 mg/liter for both isolates. Both isolates had three novel gyrA mutations (55-Leu-->Trp, 87-Asp-->Ala, and 106-Gln-->Arg) and three novel parC mutations (84-Glu-->Lys, 106-Trp-->Gly, and 128-Tyr-->Asp).

Indexed as

Drug Resistance, BacterialMutation, MissenseAdultAmino Acid SubstitutionAnti-Bacterial AgentsBacterial ProteinsBloodChild, PreschoolCiprofloxacinDNA, BacterialDNA GyraseDNA Topoisomerase IVHumansKuwaitMaleMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial ProteinsCiprofloxacinDNA, BacterialDNA GyraseDNA Topoisomerase IV

Identifiers

PMID18971360
PMCPMC2620837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.