ReviewJournal of pediatric surgery2008
Stem cells as a potential future treatment of pediatric intestinal disorders.
Review in Journal of pediatric surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Current practice and future perspectives in the treatment of short bowel syndrome in children--a systematic review.Langenbeck's archives of surgery · 2012Pooled it
- An exploratory in vitro co-culture of enteric neurons and smooth muscle cells demonstrates neuronal contribution to muscle layer formation.Scientific reports · 2026Article
- Review
- Age disparities in intestinal stem cell quantities: a possible explanation for preterm infant susceptibility to necrotizing enterocolitis.Pediatric surgery international · 2022Article
- HOPXAmerican journal of physiology. Gastrointestinal and liver physiology · 2021Article
- The emerging role of exosomes in the pathogenesis, prognosis and treatment of necrotizing enterocolitis.American journal of translational research · 2020Review
- Preservation of reserve intestinal epithelial stem cells following severe ischemic injury.American journal of physiology. Gastrointestinal and liver physiology · 2019Article
- Influence of Growth Factors on the Development of Necrotizing Enterocolitis.Clinics in perinatology · 2019Review
- Umbilical mesenchymal stromal cells provide intestinal protection through nitric oxide dependent pathways.The Journal of surgical research · 2018Article
- Advanced three-dimensional culture of equine intestinal epithelial stem cells.Equine veterinary journal · 2018Article
- Equine Intestinal Mucosal Pathobiology.Annual review of animal biosciences · 2018Review
- Stem cell therapy in necrotizing enterocolitis: Current state and future directions.Seminars in pediatric surgery · 2018Review
- Stem cells and necrotizing enterocolitis: A direct comparison of the efficacy of multiple types of stem cells.Journal of pediatric surgery · 2017Article
- Mesenchymal stromal cell therapy for the treatment of intestinal ischemia: Defining the optimal cell isolate for maximum therapeutic benefit.Cytotherapy · 2016Review
- Effects of mesenchymal stem cells and VEGF on liver regeneration following major resection.Langenbeck's archives of surgery · 2016Article
- Human Adipose Stromal Cells Increase Survival and Mesenteric Perfusion Following Intestinal Ischemia and Reperfusion Injury.Shock (Augusta, Ga.) · 2016Article
- Characterization of discrete equine intestinal epithelial cell lineages.American journal of veterinary research · 2015Article
- Intestinal stem cells and stem cell-based therapy for intestinal diseases.Cytotechnology · 2015Article
- Animal models of ischemia-reperfusion-induced intestinal injury: progress and promise for translational research.American journal of physiology. Gastrointestinal and liver physiology · 2015Review
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
All surgical disciplines encounter planned and unplanned ischemic events that may ultimately lead to cellular dysfunction and death. Stem cell therapy has shown promise for the treatment of a variety of ischemic and inflammatory disorders where tissue damage has occurred. As stem cells have proven beneficial in many disease processes, important opportunities in the future treatment of gastrointestinal disorders may exist. Therefore, this article will serve to review the different types of stem cells that may be applicable to the treatment of gastrointestinal disorders, review the mechanisms suggesting that stem cells may work for these conditions, discuss current practices for harvesting and purifying stem cells, and provide a concise summary of a few of the pediatric intestinal disorders that could be treated with cellular therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.