ArticleTalanta2005
Fluorescence sensors for monosaccharides based on the 6-methylquinolinium nucleus and boronic acid moiety: potential application to ophthalmic diagnostics.
Article in Talanta, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 85 citations in OpenAlex.
- Water-soluble fluorescent chemosensor for sorbitol based on a dicationic diboronic receptor. Crystal structure and spectroscopic studies.RSC advances · 2023Article
- Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis.Sensors (Basel, Switzerland) · 2022Article
- Colorimetric and Electrochemical Screening for Early Detection of Diabetes Mellitus and Diabetic Retinopathy-Application of Sensor Arrays and Machine Learning.Sensors (Basel, Switzerland) · 2022Review
- Comprehensive Review on Wearable Sweat-Glucose Sensors for Continuous Glucose Monitoring.Sensors (Basel, Switzerland) · 2022Review
- Ophthalmic Sensors and Drug Delivery.ACS sensors · 2021Review
- Glucose-sensitive silicone hydrogel contact lens toward tear glucose monitoring.Journal of biomedical optics · 2018Article
- Contact lens to measure individual ion concentrations in tears and applications to dry eye disease.Analytical biochemistry · 2018Article
- Glucose Sensing for Diabetes Monitoring: Recent Developments.Sensors (Basel, Switzerland) · 2017Review
- A Gelated Colloidal Crystal Attached Lens for Noninvasive Continuous Monitoring of Tear Glucose.Polymers · 2017Article
- Trends in Nanomaterial-Based Non-Invasive Diabetes Sensing Technologies.Diagnostics (Basel, Switzerland) · 2014Review
- Quantum dot nanometal surface energy transfer based biosensing of sialic acid compositions and linkages in biological samples.Analytical chemistry · 2013Article
- Toward an injectable continuous osmotic glucose sensor.Journal of diabetes science and technology · 2010Article
- Synthesis, spectroscopy and photochemistry of nitro-azobenzene dyes bearing benzophenone parts.Journal of fluorescence · 2009Article
- Measurement of glucose in blood with a phenylboronic acid optical sensor.Journal of diabetes science and technology · 2008Article
- Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA.Nucleic acids research · 2007Article
- Wavelength-ratiometric and colorimetric probes for glucose determination.Dyes and pigments : an international journal · 2006Article
- Wavelength-ratiometric near-physiological pH sensors based on 6-aminoquinolinium boronic acid probes.Talanta · 2005Article
- Enhanced fluorescence cyanide detection at physiologically lethal levels: reduced ICT-based signal transduction.Journal of the American Chemical Society · 2005Article
- A glucose-sensing contact lens: from bench top to patient.Current opinion in biotechnology · 2005Review
- OPHTHALMIC GLUCOSE MONITORING USING DISPOSABLE CONTACT LENSES.Reviews in fluorescence · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Continuous monitoring of glucose levels in human physiology is important for the long-term management of diabetes. New signaling methods/probes may provide an improved technology to monitor glucose and other physiologically important analytes. The glucose sensing probes, BMQBAs, fabricated using the 6-methylquinolinium moiety as a fluorescent indicator, and boronic acid as a chelating group, may have versatile applications in glucose sensing because of their unique properties. In this paper we discuss the design logic, synthesis, characterization and spectral properties of three new isomeric glucose sensors (BMQBAs), and a control compound (BMQ) in the presence and absence of sugars. The sensing ability of the new probes is based on a charge neutralization and stabilization mechanism upon sugar binding. The new probes have attractive fluorescence quantum yields, are highly water-soluble, and have spectral characteristics compatible with cheap and portable LEDs and LDs. One of the probes, o-BMQBA, has a sugar bound pK(a) of 6.1, and a dissociation constant K(D) of 100mM glucose. These probes have been designed specifically to respond to tear glucose in a contact lens polymer for ophthalmic glucose monitoring, where the reduced sugar bound pK(a) affords for sensing, in a lens environment that we have previously shown to be mildly acidic.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.