ReviewCurrent hypertension reports2008
Genetic determinants of hypertension: an update.
Review in Current hypertension reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The role of cytochrome P450 gene rs1126742 polymorphism and risk of hypertension: a systematic review and meta-analysis.Bioscience reports · 2020Pooled it
- Evidence on the causal link between homocysteine and hypertension from a meta-analysis of 40 173 individuals implementing Mendelian randomization.Journal of clinical hypertension (Greenwich, Conn.) · 2019Pooled it
- Associations between polymorphisms of the ADIPOQ gene and hypertension risk: a systematic and meta-analysis.Scientific reports · 2017Pooled it
- Genetic associations with hypertension: meta-analyses of six candidate genetic variants.Genetic testing and molecular biomarkers · 2013Pooled it
- Associations of polymorphisms in the β2-adrenergic receptor gene with essential hypertension in Han Chinese population.Molecular biology reports · 2012Pooled it
- Common polymorphisms (rs2241766 and rs1501299) in the ADIPOQ gene are not associated with hypertension susceptibility among the Chinese.Molecular biology reports · 2012Pooled it
- Differences in the genotype frequencies of genes related to blood pressure regulation - a comparative study between South-West Europe and Peri-equatorial Africa.African health sciences · 2021Article
- Association of single nucleotide polymorphisms inInternational journal of molecular epidemiology and genetics · 2021Review
- Association between serotonin 2A receptor (HTR2A) genetic variations and risk of hypertension in a community-based cohort study.BMC medical genetics · 2020Article
- Effects of Red Palm Oil on Myocardial Antioxidant Enzymes, Nitric Oxide Synthase and Heart Function in Spontaneously Hypertensive Rats.International journal of molecular sciences · 2017Article
- Association of four insulin resistance genes with type 2 diabetes mellitus and hypertension in the Chinese Han population.Molecular biology reports · 2014Article
- Construction and analysis of the protein-protein interaction network related to essential hypertension.BMC systems biology · 2013Article
- Impact of a novel mutation in the 5'-flanking region of natriuretic peptide precursor B gene on the antihypertensive effects of sodium nitroprusside in patients with hypertension.Journal of human hypertension · 2013Article
- Inflammation and hypertension: are there regional differences?International journal of hypertension · 2013Article
- Dopamine, the kidney, and hypertension.Current hypertension reports · 2012Review
- Abnormalities in renal dopamine signaling and hypertension: the role of GRK4.Current opinion in nephrology and hypertension · 2012Review
- Dopamine and renal function and blood pressure regulation.Comprehensive Physiology · 2011Review
- Dopamine and G protein-coupled receptor kinase 4 in the kidney: role in blood pressure regulation.Biochimica et biophysica acta · 2010Review
- Opportunities and limitations of genetic analysis of hypertensive rat strains.Journal of hypertension · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension represents a global public health burden. In addition to the rarer Mendelian forms of hypertension, classic genetic studies have documented a significant heritable component to the most common form, essential hypertension (EH). Extensive efforts are under way to elucidate the genetic basis of this disease. Recently, a new form of Mendelian hypertension has been identified, pharmacogenetic association studies in hypertensive patients have identified novel gene-by-drug interactions, and the first genome-wide association studies of EH have been published. New findings in consomic and congenic rat models also offer new clues to the genetic architecture of this complex phenotype. In this review, the authors summarize and evaluate the most recent findings related to hypertension gene identification.
Indexed as
Identifiers
18959837What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.