Evidence map›Paper›PMID 18958461›Full record

ArticleNeuroradiology2009

Serial proton MR spectroscopy and diffusion tensor imaging in infantile Balo's concentric sclerosis.

Steffi F Dreha-Kulaczewski, Gunther Helms, Peter Dechent, Sabine Hofer, Jutta Gärtner, Jens Frahm

Erratum issuedOpen access · hybridAbstract readCase Reports
In one paragraph

Article in Neuroradiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Knowledge and awareness on Balo's disease among dental students: A survey.Journal of advanced pharmaceutical technology & research · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Steffi F Dreha-KulaczewskiDepartment of Pediatrics and Pediatric Neurology, Georg August University, Göttingen, Germany. sdreha@gwdg.de
Gunther Helms
Peter Dechent
Sabine Hofer
Jutta Gärtner
Jens Frahm
University of Göttingen · DEMax Planck Institute for Biophysical Chemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionProton magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI) yield different parameters for characterizing the evolution of a demyelinating white matter disease. The purpose was to elucidate biochemical and microstructural changes in Balo's concentric sclerosis lesions and to correlate the findings with the clinical course.

methodsLocalized short-echo time MRS and DTI were performed over 6 years in a left occipital lesion of a female patient (age at onset 13.8 years) with Balo's concentric sclerosis. A right homonym hemianopsia persisted.

resultsMetabolite patterns were in line with initial active demyelination followed by gliosis and partial recovery of neuroaxonal metabolites. Fractional anisotropy and mean diffusivity of tissue water remained severely altered. Fiber tracking confirmed a disruption in the geniculo-calcarine tract as well as involvement of the corpus callosum.

conclusionMRS and DTI depict complementary parameters, but DTI seems to correlate better with clinical symptoms.

Indexed as

AdolescentBrainDiffuse Cerebral Sclerosis of SchilderFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyProtonsTissue DistributionProtons

Identifiers

PMID18958461
PMCPMC2726919
OpenAlexW2068206909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.