Evidence map›Paper›PMID 18958362›Full record

ReviewSheng li xue bao : [Acta physiologica Sinica]2008

Postnatal roles of glial cell line-derived neurotrophic factor family members in nociceptors plasticity.

Sacha A Malin, Brian M Davis

Open access · greenAbstract readReview
In one paragraph

Review in Sheng li xue bao : [Acta physiologica Sinica], 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. GDNF, Neurturin, and Artemin Activate and Sensitize Bone Afferent Neurons and Contribute to Inflammatory Bone Pain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  3. TFOS DEWS II pain and sensation report.The ocular surface · 2017
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. RET signaling is required for survival and normal function of nonpeptidergic nociceptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sacha A MalinDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Brian M Davis
University of Pittsburgh · US

Funding

Characterization and Plasticity of Visceral NociceptorsR01NS050758 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVIS, BRIAN M · 2005 to 2012
$2.6M
NINDS NIH HHS R01 NS050758
6 · The paper itself

Abstract

The neurotrophin and glial cell line-derived neurotrophic factor (GDNF) family of growth factors have been extensively studied because of their proven ability to regulate development of the peripheral nervous system. The neurotrophin family, which includes nerve growth factor (NGF), NT-3, NT4/5 and BDNF, is also known for its ability to regulate the function of adult sensory neurons. Until recently, little was known concerning the role of the GNDF-family (that includes GDNF, artemin, neurturin and persephin) in adult sensory neuron function. Here we describe recent data that indicates that the GDNF family can regulate sensory neuron function, that some of its members are elevated in inflammatory pain models and that application of these growth factors produces pain in vivo. Finally we discuss how these two families of growth factors may converge on a single membrane receptor, TRPV1, to produce long-lasting hyperalgesia.

Indexed as

AnimalsGlial Cell Line-Derived Neurotrophic FactorsHumansHyperalgesiaNerve Tissue ProteinsNeurturinNociceptorsTRPV Cation ChannelsGlial Cell Line-Derived Neurotrophic FactorsNerve Tissue ProteinsNeurturinpersephinTRPV Cation Channels

Identifiers

PMID18958362
PMCPMC2677061
OpenAlexW189974180

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.