ArticleFrontiers in integrative neuroscience2007
Spontaneous electrical activity and behavior in the leech hirudo medicinalis.
Article in Frontiers in integrative neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Is criticality a unified setpoint of brain function?Neuron · 2025Pooled it
- Ultrasound Stimulations Induce Prolonged Depolarization and Fast Action Potentials in Leech Neurons.IEEE open journal of engineering in medicine and biology · 2020Article
- Association between Scale-Free Brain Dynamics and Behavioral Performance: Functional MRI Study in Resting State and Face Processing Task.Behavioural neurology · 2017Article
- Effects of millimeter wave irradiation and equivalent thermal heating on the activity of individual neurons in the leech ganglion.Journal of neurophysiology · 2014Article
- Scanning behavior in the medicinal leech Hirudo verbana.PloS one · 2014Article
- An accumulator model for spontaneous neural activity prior to self-initiated movement.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Scale-free properties of the functional magnetic resonance imaging signal during rest and task.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Readiness discharge for spontaneous initiation of walking in crayfish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
In the absence of external stimuli, animals explore the environment by performing irregular movements, but the neuronal mechanisms underlying this arrhythmic motion are largely unknown. In this paper, we studied the relationship between the spontaneous neuronal activity in the leech (Hirudo medicinalis) and its behavior. We analyzed the electrical activity of isolated ganglia, chains of two connected ganglia, and semi-intact preparations. The spontaneous electrical activity in ganglia was characterized by the occurrence of irregular bursts of spikes with variable duration and size. Properties of these bursts were modified by synaptic inputs arriving from the neighboring ganglia and from the two primitive brains located in the head and tail. In fact, in semi-intact preparations, unusually large bursts of spikes occurring spontaneously were recorded and caused the leech to move even in the absence of any external sensory stimulation. These large bursts appear to act as internal triggers controlling the spontaneous leech behavior and determining the duration of stereotypical motor patterns.
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Registered trials
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