SynthesisJournal of genetic counseling2008
A systematic review of the effects of disclosing carrier results generated through newborn screening.
Synthesis in Journal of genetic counseling, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Data-Related and Methodological Challenges in Assessing the Cost-Effectiveness of Traditional and Genomic Newborn Screening Programs.Applied health economics and health policy · 2026Review
- Understanding the psychological impact of identifying carrier status on young adults: A qualitative study exploring peer reactions.Journal of genetic counseling · 2025Article
- Health services use by children identified as heterozygous hemoglobinopathy mutation carriers via newborn screening.BMC pediatrics · 2021Article
- Newborn screening for cystic fibrosis: Role of primary care providers in caring for infants with positive screening results.Canadian family physician Medecin de famille canadien · 2021Article
- Coming to terms with the imperfectly normal child: attitudes of Israeli parents of screen-positive infants regarding subsequent prenatal diagnosis.Journal of community genetics · 2019Article
- Genetic Counselors' Experience with and Opinions on the Management of Newborn Screening Incidental Carrier Findings.Journal of genetic counseling · 2018Article
- A secondary benefit: the reproductive impact of carrier results from newborn screening for cystic fibrosis.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Article
- Genomic newborn screening: public health policy considerations and recommendations.BMC medical genomics · 2017Article
- Prevalence of Sickle Cell Trait and Reliability of Self-Reported Status among Expectant Parents in Nigeria: Implications for Targeted Newborn Screening.Public health genomics · 2016Article
- Article
- Parents' responses to receiving sickle cell or cystic fibrosis carrier results for their child following newborn screening.European journal of human genetics : EJHG · 2015Article
- Disparities in current and future childhood and newborn carrier identification.Journal of genetic counseling · 2014Article
- Informing children of their newborn screening carrier result for sickle cell or cystic fibrosis: qualitative study of parents' intentions, views and support needs.Journal of genetic counseling · 2014Article
- Parental knowledge reduces long term anxiety induced by false-positive test results after newborn screening for cystic fibrosis.Molecular genetics and metabolism reports · 2014Article
- Understanding sickle cell carrier status identified through newborn screening: a qualitative study.European journal of human genetics : EJHG · 2010Article
- Commentary: a sociologist's view on community genetics.Journal of community genetics · 2010Article
- Non-invasive prenatal testing: ethical issues explored.European journal of human genetics : EJHG · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence on the effects of disclosing carrier results identified through newborn screening (NBS) is needed to develop effective strategies for managing these results, and to inform debate about contradictory policies governing genetic testing in minors in the context of NBS relative to clinical care. This is likely to be even more important as technological opportunities for carrier identification through NBS increase. We report the results of a systematic review of evidence related to the generation of carrier results through NBS to summarize what is known about: (1) the outcomes associated with these results; (2) the best strategies for providing information and follow-up care to parents; and (3) the impact they have on reproductive decision-making. Our study expands the existing body of knowledge and identifies gaps in the evidence base. As key players in the management of carrier results clinically, genetic counselors are well positioned to engage in formative research and policy development in this area.
Indexed as
Identifiers
18956236What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.