Evidence map›Paper›PMID 18955729›Full record

ReviewJournal of lipid research2009

Regulation of phospholipid synthesis in yeast.

George M Carman, Gil-Soo Han

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of lipid research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 123 citations in OpenAlex.

  1. Article
  2. Unravelling the Molecular Responses of the YeastInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Phosphatidylcholine biosynthesis pathways inFrontiers in cellular and infection microbiology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Phosphatidate-mediated regulation of lipid synthesis at the nuclear/endoplasmic reticulum membrane.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

George M CarmanDepartment of Food Science and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ 08901, USA. carman@aesop.rutgers.edu
Gil-Soo Han
Rutgers, The State University of New Jersey · US

Funding

REGULATION OF PHOSPHOLIPID SYNTHESIS BY CTPR01GM050679 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI CARMAN, GEORGE M. · 1994 to 2019
$6.0M
Phospholipid metabolism and membrane functionR37GM028140 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI CARMAN, GEORGE M. · 2010 to 2019
$4.0M
PHOSPHOLIPID METABOLSIM AND MEMBRANE FUNCTIONR01GM028140 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI CARMAN, GEORGE M. · 1985 to 2009
$3.2M
NIGMS NIH HHS GM-28140NIGMS NIH HHS GM-50679NIGMS NIH HHS R01 GM028140
6 · The paper itself

Abstract

Phospholipid synthesis in the yeast Saccharomyces cerevisiae is a complex process that involves regulation by both genetic and biochemical mechanisms. The activity levels of phospholipid synthesis enzymes are controlled by gene expression (e.g., transcription) and by factors (lipids, water-soluble phospholipid precursors and products, and covalent modification of phosphorylation) that modulate catalysis. Phosphatidic acid, whose levels are controlled by the biochemical regulation of key phospholipid synthesis enzymes, plays a central role in the regulation of phospholipid synthesis gene expression.

Indexed as

Diacylglycerol KinaseInositolPhosphatidic AcidsPhospholipidsSaccharomyces cerevisiaeZincDiacylglycerol KinaseInositolPhosphatidic AcidsPhospholipidsZinc

Identifiers

PMID18955729
PMCPMC2674725
OpenAlexW2052836755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.