ArticleEvidence-based complementary and alternative medicine : eCAM2010
In vitro Evaluation of the Antiviral Activity of an Extract of Date Palm (Phoenix dactylifera L.) Pits on a Pseudomonas Phage.
Article in Evidence-based complementary and alternative medicine : eCAM, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Harnessing the power of date fruit: nutritional, bioactive, and functional roles in sustainable nutrition.Biodegradation · 2026Review
- Date palm fruits (Frontiers in plant science · 2026Review
- Nutraceuticals ofDrug design, development and therapy · 2026Review
- Network Pharmacology andCurrent pharmaceutical design · 2025Article
- Ajwa date extract (Saudi medical journal · 2025Article
- Phytochemical profiling ofRSC advances · 2024Article
- Article
- The use of plant extracts and bacteriophages as an alternative therapy approach in combatting bacterial infections: the study of lytic phages andJournal of veterinary research · 2023Article
- Date Palm Fruit (Nutrients · 2023Review
- Biochemical Composition and Biological Activities of Date Palm (Biomolecules · 2022Review
- Bioactivity and Pharmacological Potential of Date Palm (Phoenix dactylifera L.) Against Pandemic COVID-19: a Comprehensive Review.Applied biochemistry and biotechnology · 2022Review
- Investigation of Hematological and Biochemical Effects of Feeding Date in the Early Morning on Empty Stomach vs. after Nutrition on Rabbits.Archives of Razi Institute · 2022Article
- Cytotoxic and Antioxidant Effects of Phoenix dactylifera L. (Ajwa Date Extract) on Oral Squamous Cell Carcinoma Cell Line.BioMed research international · 2022Article
- Improving Phage-Biofilm In Vitro Experimentation.Viruses · 2021Article
- Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm.Biochemistry and biophysics reports · 2021Article
- Effect of Date Palm Pollen Supplementation on the Egg Production, Ovarian Follicles Development, Hematological Variables and Hormonal Profile of Laying Hens.Animals : an open access journal from MDPI · 2021Article
- Anti-inflammatory activity of date palm seed by downregulating interleukin-1β, TGF-β, cyclooxygenase-1 and -2: A study among middle age women.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- Phytotherapeutic potential and pharmaceutical impact ofJournal of food science and technology · 2020Review
- Effect of a diet containing date pits on growth performance, diet digestibility, and economic evaluation of Japanese quail (Coturnix coturnix japonica).Tropical animal health and production · 2020Article
- Evaluation of the level of biomolecules isolated from date palm seeds (BioMedicine · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A crude acetone extract of the pit of date palm (Phoenix dactylifera L.) was prepared and its antiviral activity evaluated against lytic Pseudomonas phage ATCC 14209-B1, using Pseudomonas aeruginosa ATCC 25668 as the host cell. The antiviral activity of date pits was found to be mediated by binding to the phage, with minimum inhibitory concentration (MIC) of <10 μg ml(-1). The decimal reduction time (D-values), the concentration exponent (η) and the phage inactivation kinetics were determined. The date pit extracts show a strong ability to inhibit the infectivity of Pseudomonas phage ATCC 14209-B1 and completely prevented bacterial lysis, which it is hoped will promote research into its potential as a novel antiviral agent against pathogenic human viruses.
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Registered trials
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