ArticleEvidence-based complementary and alternative medicine : eCAM2009
Ficus racemosa Stem Bark Extract: A Potent Antioxidant and a Probable Natural Radioprotector.
Article in Evidence-based complementary and alternative medicine : eCAM, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 104 citations in OpenAlex.
- Harnessing animal model and computational experiments to discover antidiabetic compounds in Ficus racemosa.BMC complementary medicine and therapies · 2025Article
- Natural Guardians: Natural Compounds as Radioprotectors in Cancer Therapy.International journal of molecular sciences · 2024Review
- Bioactive Constituents and Toxicological Evaluation of Selected Antidiabetic Medicinal Plants of Saudi Arabia.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Antioxidant and Antiproliferative Potentials ofPharmaceuticals (Basel, Switzerland) · 2021Article
- Was Hawan Designed to Fight Anxiety-Scientific Evidences?Journal of religion and health · 2020Review
- Pharmacology of natural radioprotectors.Archives of pharmacal research · 2018Review
- Oral Administration of Vitamin C, Cimetidine and Famotidine on Micronuclei Induced by Low Dose Radiation in Mouse Bone Marrow Cells.Journal of biomedical physics & engineering · 2017Article
- In vitro free radical scavenging activity of ethanolic extract of the whole plant of Evolvulus alsinoides (L.) L.Chinese journal of integrative medicine · 2015Article
- Antioxidant, Biomolecule Oxidation Protective Activities of Nardostachys jatamansi DC and Its Phytochemical Analysis by RP-HPLC and GC-MS.Antioxidants (Basel, Switzerland) · 2015Article
- Preliminary phytochemical screening and in vitro antioxidant activities of Parkinsonia aculeata Linn.BioMed research international · 2014Article
- Evaluation of hepatic antioxidant capacities of Spirogyra neglecta (Hassall) Kützing in rats.Interdisciplinary toxicology · 2013Article
- Studies on black tea (Camellia sinensis) extract as a potential antioxidant and a probable radioprotector.Radiation and environmental biophysics · 2013Article
- Redox Mechanisms of AVS022, an Oriental Polyherbal Formula, and Its Component Herbs in Protection against Induction of Matrix Metalloproteinase-1 in UVA-Irradiated Keratinocyte HaCaT Cells.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Antioxidant activities of licorice-derived prenylflavonoids.Nutrition research and practice · 2012Article
- Radioprotection by Macerated Extract of Nigella sativa in Normal Tissues of Fibrosarcoma Bearing Mice.Indian journal of pharmaceutical sciences · 2012Article
- In vitro antioxidant and antiproliferative potential of medicinal plants used in traditional Indian medicine to treat cancer.Redox report : communications in free radical research · 2012Article
- Phytochemical constituents and antioxidant activities of the whole leaf extract of Aloe ferox Mill.Pharmacognosy magazine · 2011Article
- Metabolic Profile of Offspring from Diabetic Wistar Rats Treated with Mentha piperita (Peppermint).Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Anti-Oxidative Abilities of Essential Oils from Atractylodes ovata Rhizome.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- REC-2006-A Fractionated Extract of Podophyllum hexandrum Protects Cellular DNA from Radiation-Induced Damage by Reducing the Initial Damage and Enhancing Its Repair In Vivo.Evidence-based complementary and alternative medicine : eCAM · 2011Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethanol extract (FRE) and water extract (FRW) of Ficus racemosa (family: Moraceae) were subjected to free radical scavenging both by steady state and time resolved methods such as nanosecond pulse radiolysis and stopped-flow spectrophotometric analyses. FRE exhibited significantly higher steady state antioxidant activity than FRW. FRE exhibited concentration dependent DPPH, ABTS(*-), hydroxyl radical and superoxide radical scavenging and inhibition of lipid peroxidation with IC(50) comparable with tested standard compounds. In vitro radioprotective potential of FRE was studied using micronucleus assay in irradiated Chinese hamster lung fibroblast cells (V79). Pretreatment with different doses of FRE 1h prior to 2 Gy gamma-radiation resulted in a significant (P < 0.001) decrease in the percentage of micronucleated binuclear V79 cells. Maximum radioprotection was observed at 20 mug/ml of FRE. The radioprotection was found to be significant (P < 0.01) when cells were treated with optimum dose of FRE (20 mug/ml) 1 h prior to 0.5, 1, 2, 3 and 4 Gy gamma-irradiation compared to the respective radiation controls. The cytokinesis-block proliferative index indicated that FRE does not alter radiation induced cell cycle delay. Based on all these results we conclude that the ethanol extract of F. racemosa acts as a potent antioxidant and a probable radioprotector.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.