ReviewCurrent opinion in microbiology2008
Fungal adaptation to the mammalian host: it is a new world, after all.
Review in Current opinion in microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- The antiparasitic drug Nitazoxanide enhances the susceptibility of Candida albicans to fluconazole.BMC microbiology · 2026Article
- Harnessing Fungi Signaling in Living Composites.Global challenges (Hoboken, NJ) · 2024Article
- VmPacC-mediated pH regulation of Valsa mali confers to host acidification identified by comparative proteomics analysis.Stress biology · 2023Article
- An in vitro method for inducing titan cells reveals novel features of yeast-to-titan switching in the human fungal pathogen Cryptococcus gattii.PLoS pathogens · 2022Article
- Biologia futura: combinatorial stress responses in fungi.Biologia futura · 2022Review
- Drk1, a Dimorphism Histidine Kinase, Contributes to Morphology, Virulence, and Stress Adaptation inJournal of fungi (Basel, Switzerland) · 2021Article
- Transcriptome Analysis of Dimorphic Fungus Sporothrix schenckii Exposed to Temperature Stress.International microbiology : the official journal of the Spanish Society for Microbiology · 2021Article
- Targeting Unconventional Pathways in Pursuit of Novel Antifungals.Frontiers in molecular biosciences · 2020Review
- Calcium-Calmodulin-Calcineurin Signaling: A Globally Conserved Virulence Cascade in Eukaryotic Microbial Pathogens.Cell host & microbe · 2019Review
- Protein Kinases at the Intersection of Translation and Virulence.Frontiers in cellular and infection microbiology · 2019Review
- Evasion of Immune Surveillance in Low Oxygen Environments Enhances Candida albicans Virulence.mBio · 2018Article
- Life in the cystic fibrosis upper respiratory tract influences competitive ability of the opportunistic pathogenRoyal Society open science · 2018Article
- Two‑component histidine kinase DRK1 is required for pathogenesis in Sporothrix schenckii.Molecular medicine reports · 2018Article
- The Hsp90 Chaperone Network Modulates Candida Virulence Traits.Trends in microbiology · 2017Review
- Metabolic Interactions between Bacteria and Fungi in Commensal Oral Biofilms.Journal of fungi (Basel, Switzerland) · 2017Review
- Specificity of genome evolution in experimental populations ofProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Article
- Evolution of Bacterial Pathogens Within the Human Host.Microbiology spectrum · 2016Review
- Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer.Nanoscale research letters · 2015Article
- Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus.PLoS neglected tropical diseases · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Adaptation to environmental conditions is key to fungal survival during infection of human hosts. Although the host immune system is often considered the primary obstacle to fungal colonization, invading fungi must also contend with extreme abiotic stresses. Recent work with human pathogenic fungi has uncovered systems for detecting and responding to changes in temperature, carbon source, metal ion availability, pH, and gas tension. These systems play a major role in adaptation to the host niche and are essential factors for persistence in a mammalian host. Future investigations into fungal responses to these and other abiotic components of the host environment have the potential to uncover novel targets for anti-fungal therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.