Evidence map›Paper›PMID 18955146›Full record

ArticleMethods (San Diego, Calif.)2009

Technical considerations in using DNA microarrays to define regulons.

Virgil A Rhodius, Joseph T Wade

Abstract read
In one paragraph

Article in Methods (San Diego, Calif.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Photomorphogenesis of Myxococcus macrosporus: new insights for light-regulation of cell development.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Virgil A RhodiusDepartment of Microbiology and Immunology, University of California at San Francisco, San Francisco, CA 94143, USA. virgil.rhodius@ucsf.edu
Joseph T Wade
University of California, San Francisco · USWadsworth Center · US

Funding

MUTATIONAL ANALYSIS OF E COLI CORE RNA POLYMERASER01GM057755 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GROSS, CAROL ANNE · 1998 to 2013
$6.2M
NIGMS NIH HHS GM57755NIGMS NIH HHS R01 GM057755
6 · The paper itself

Abstract

Transcription is the major regulatory target of gene expression in bacteria, and is controlled by many regulatory proteins and RNAs. Microarrays are a powerful tool to study the regulation of transcription on a genomic scale. Here we describe the use of transcription profiling and ChIP-chip to study transcriptional regulation in bacteria. Transcription profiling determines the outcome of regulatory events whereas ChIP-chip identifies the protein-DNA interactions that determine these events. Together they can provide detailed information on transcriptional regulatory systems.

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsChromatin ImmunoprecipitationComputational BiologyGene Expression ProfilingOligonucleotide Array Sequence AnalysisProtein BindingRegulonBacterial Proteins

Identifiers

PMID18955146
PMCPMC2637246
OpenAlexW2088973078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.