ArticleThe American journal of medicine2008
The comorbidity of diabetes mellitus and depression.
Article in The American journal of medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01781013 (Care Management Technology to Facilitate Depression Care in Safety Net Diabetes Clinics), which is not on this map. Cited by 123 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Care Management Technology to Facilitate Depression Care in Safety Net Diabetes Clinics
Who cites it
123 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Treatment for comorbid depressive disorder or subthreshold depression in diabetes mellitus: Systematic review and meta-analysis.Brain and behavior · 2021Pooled it
- Depression in Turner Syndrome: A Systematic Review.Archives of sexual behavior · 2020Pooled it
- Quality indicators for care of depression in primary care settings: a systematic review.Systematic reviews · 2017Pooled it
- Depression and adherence to treatment in diabetic children and adolescents: a systematic review and meta-analysis of observational studies.European journal of pediatrics · 2014Pooled it
- Trial
- Comparative Effectiveness of a Technology-Facilitated Depression Care Management Model in Safety-Net Primary Care Patients With Type 2 Diabetes: 6-Month Outcomes of a Large Clinical Trial.Journal of medical Internet research · 2018Trial
- Trial
- Trial
- A randomized trial of telephonic counseling plus walking for depressed diabetes patients.Medical care · 2011Trial
- Depressive symptom deterioration among predominantly Hispanic diabetes patients in safety net care.PsychosomaticsTrial
- Depression remission, receipt of problem-solving therapy, and self-care behavior frequency among low-income, predominantly Hispanic diabetes patients.General hospital psychiatryTrial
- Sotagliflozin pretreatment attenuates acute LPS-induced depression-like behavioral abnormalities and modulates the gut microbiota-immune-brain axis.Psychopharmacology · 2026Article
- Systematic review and meta-analysis on depression burden among Type 2 diabetes patients in India.Diabetology & metabolic syndrome · 2026Review
- Article
- Integrated management of dry eye-depression comorbidity: mechanistic insights and temporal therapeutic strategies.Frontiers in medicine · 2026Article
- Article
- Mechanisms and Pathways Linking Depression and Type 2 Diabetes Outcomes: A Scoping Review.Journal of diabetes research · 2025Article
- Comparison of Diabetes Education Content Experienced by Blind and Nonblind People With Diabetes.Clinical diabetes : a publication of the American Diabetes Association · 2025Article
- Association of systemic immune inflammation index with depression among adult type 2 diabetic patients in a tertiary hospital, Ethiopia, 2022.Frontiers in endocrinology · 2025Article
- The effect of socioeconomic status, depression, and diabetes symptoms severity on diabetes patient's life satisfaction in India.Scientific reports · 2024Article
63 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Several factors, including sedentary lifestyle, obesity, and an aging population, contribute to epidemic rates of type 2 diabetes mellitus. Depression frequently occurs comorbidly with diabetes although it is unrecognized and untreated in approximately two thirds of patients with both conditions. The course of depression in patients with both diabetes and depression is chronic and severe. Up to 80% of patients with diabetes and depression will experience a relapse of depressive symptoms over a 5-year period. Depression is associated with nonadherence to diabetes self-care--including following dietary restrictions, medication compliance, and blood glucose monitoring--resulting in worse overall clinical outcomes. Due to potential negative health consequences associated with comorbid diabetes and depression, both conditions should be optimally treated to maximize patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.