Evidence map›Paper›PMID 1895405›Full record

ArticleJournal of virology1991

Moloney leukemia virus immortalizes B lymphocytes in vitro.

J Runnels, L Serunian, M Thursby, N Rosenberg

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

J RunnelsDepartment of Pathology, Tufts University School of Medicine, Boston, Massachusetts 02111.
L Serunian
M Thursby
N Rosenberg
Tufts University · US

Funding

REGULATION OF IMMUNOGLOBULIN SYNTHESISP01CA024530 · NCI · TUFTS UNIVERSITY BOSTON · PI COFFIN, JOHN M · 1985 to 1992
–
NCI NIH HHS CA 24530
6 · The paper itself

Abstract

An in vitro culture system in which Moloney murine leukemia virus induces immortalization of mature B lymphocytes has been developed. The cell lines derived in this way are nontumorigenic, and virus production is not required to sustain them. This system provides a new in vitro model with which to study the stepwise process of transformation by retroviruses lacking oncogenes.

Indexed as

Cell Transformation, ViralAnimalsB-LymphocytesBone Marrow CellsCell LineCells, CulturedKineticsLipopolysaccharidesMiceMoloney murine leukemia virusTime FactorsViral ProteinsLipopolysaccharidesViral Proteins

Identifiers

PMID1895405
PMCPMC249058
OpenAlexW1514202672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.