Evidence map›Paper›PMID 18953522›Full record

ReviewDer Urologe. Ausg. A2008

[Genetics of male infertility].

F Tüttelmann, J Gromoll, S Kliesch

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Urologe. Ausg. A, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Microtubular Dysfunction and Male Infertility.The world journal of men's health · 2020
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. [Testosterone and infertility].Der Urologe. Ausg. A · 2010
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

F TüttelmannInstitut für Humangenetik, Westfälische Wilhelms-Universität, Münster.
J Gromoll
S Kliesch
University of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic causes of male infertility increase in frequency with decreasing sperm concentration (oligo-/azoospermia). The decision about genetic tests should be made after a complete andrological work-up. Common causes comprise chromosomal aberrations (including Klinefelter syndrome), microdeletions of the AZF loci of the Y chromosome, mutations in the gene responsible for cystic fibrosis (CFTR) causing CBAVD and in genes involved in hypogonadotropic hypogonadism (including Kallmann syndrome). Every genetic investigation should be accompanied by comprehensive genetic counselling to help with the interpretation of results and support the patient/the couple concerning consequences for their family planning and treatment options.

Indexed as

AzoospermiaChromosome AberrationsChromosomes, Human, YCystic Fibrosis Transmembrane Conductance RegulatorDNA Mutational AnalysisGenetic CounselingGenetic LociHumansHypogonadismInfertility, MaleKallmann SyndromeKlinefelter SyndromeMaleSeminal Plasma ProteinsSex Chromosome AberrationsVas DeferensCystic Fibrosis Transmembrane Conductance RegulatorSeminal Plasma Proteins

Identifiers

PMID18953522
OpenAlexW138028103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.