Evidence map›Paper›PMID 18952570›Full record

ReviewJournal of lipid research2009

Membrane phospholipid synthesis and endoplasmic reticulum function.

Paolo Fagone, Suzanne Jackowski

Abstract readReview
In one paragraph

Review in Journal of lipid research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 227 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
227citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

227 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Endoplasmic reticulum in oocytes: spatiotemporal distribution and function.Journal of assisted reproduction and genetics · 2023
    Pooled it
  2. Review
  3. Article
  4. Article
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  6. Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  7. Review
  8. Article
  9. Review
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  11. The molecular mechanism of lipid uptake by membrane-anchored bridge-like lipid transfer proteins.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Review
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  18. Article
  19. Article
  20. Article

167 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paolo FagoneDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, USA.
Suzanne Jackowski

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Regulation of Coenzyme A Levels by Pantothenate KinaseR01GM062896 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI JACKOWSKI, SUZANNE · 2002 to 2014
$4.0M
Regulation of Phospholipid SynthesisR01GM045737 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI JACKOWSKI, SUZANNE · 1991 to 2006
$2.2M
NCI NIH HHS CA21765NIGMS NIH HHS GM-45737NIGMS NIH HHS R01 GM045737NIGMS NIH HHS R01 GM062896
6 · The paper itself

Abstract

This review presents an overview of mammalian phospholipid synthesis and the cellular locations of the biochemical activities that produce membrane lipid molecular species. The generalized endoplasmic reticulum compartment is a central site for membrane lipid biogenesis, and examples of the emerging relationships between alterations in lipid composition, regulation of membrane lipid biogenesis, and cellular secretory function are discussed.

Indexed as

AnimalsEndoplasmic ReticulumGolgi ApparatusMembrane LipidsPhospholipidsMembrane LipidsPhospholipids

Identifiers

PMID18952570
PMCPMC2674712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.