Evidence map›Paper›PMID 18951331›Full record

ReviewSeminars in reproductive medicine2008

Regulation of uterine matrix metalloproteinase-9 and the role of microRNAs.

Warren B Nothnick

Abstract readReview
In one paragraph

Review in Seminars in reproductive medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

  1. Matrix Metallopeptidase 9 Promotes Contraction in Human Uterine Myometrium.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Menstruation Dysregulation and Endometriosis Development.Frontiers in reproductive health · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Non-coding RNAs in Uterine Development, Function and Disease.Advances in experimental medicine and biology · 2016
    Review
  15. Molecular Characterization of Macrophage-Biomaterial Interactions.Advances in experimental medicine and biology · 2015
    Review
  16. Article
  17. Article
  18. Article
  19. Minireview: The roles of small RNA pathways in reproductive medicine.Molecular endocrinology (Baltimore, Md.) · 2011
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Warren B NothnickDepartments of Obstetrics & Gynecology and Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA. wnothnic@kumc.edu
University of Kansas Medical Center · US

Funding

Estrogen regulation of uterine microRNAs: Novel factors in MMP-9 regulationR21HD056387 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NOTHNICK, WARREN B · 2007 to 2008
$401k
NICHD NIH HHS HD056387NICHD NIH HHS R21 HD056387
6 · The paper itself

Abstract

Controlled expression of matrix metalloproteinase-9 (MMP9) is vital for normal uterine physiology, whereas abnormal expression of MMP9 is associated with uterine disease. Despite the importance of MMP9 within the uterus, its regulation is poorly understood. In this review, the complex regulation of MMP9 within the uterus is highlighted, and the potential novel role of microRNAs in the regulation of this protease is discussed. Emphasis is placed on the necessity to enhance our understanding of the regulation of MMP9 expression, which may lead to the establishment of novel approaches to counteract misexpression of this protease and the diseases associated with it.

Indexed as

Gene Expression Regulation, EnzymologicAnimalsFemaleHumansMatrix Metalloproteinase 9MicroRNAsModels, BiologicalProtein BiosynthesisUterusMatrix Metalloproteinase 9MicroRNAs

Identifiers

PMID18951331
PMCPMC4082683
OpenAlexW2068448088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.