ReviewSeminars in reproductive medicine2008
MicroRNA signature and regulatory functions in the endometrium during normal and disease states.
Review in Seminars in reproductive medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 134 citations in OpenAlex.
- Circulating microRNAs as Potential Biomarkers for the Diagnosis of Endometrial Cancer: a Meta-Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2023Pooled it
- Effect of luteal-phase support on endometrial microRNA expression following controlled ovarian stimulation.Reproductive biology and endocrinology : RB&E · 2012Trial
- Placental miRNA profiling in assisted reproductive technology (ART) pregnancies.Journal of assisted reproduction and genetics · 2025Article
- miRNA in Endometriosis-A New Hope or an Illusion?Journal of clinical medicine · 2025Review
- Cell-free pregnancy-associated microRNAs in blood plasma as potential biomarker in early diagnosis of ectopic pregnancy.Archives of gynecology and obstetrics · 2024Article
- Diagnostic Value and Molecular Function of MicroRNAs in Endometrial Diseases: A Systematic Review.Cancers · 2024Review
- MiRNAs related in signaling pathways of women's reproductive diseases: an overview.Molecular biology reports · 2024Review
- From Genes to Therapy: Pituitary Adenomas in the Era of Precision Medicine.Biomedicines · 2023Review
- Roles of microRNAs in Regulating Apoptosis in the Pathogenesis of Endometriosis.Life (Basel, Switzerland) · 2022Review
- MicroRNAs in the Regulation of Endometrial Receptivity for Embryo Implantation.International journal of molecular sciences · 2022Review
- Spatiotemporal expression pattern of miR-205, miR-26a-5p, miR-17-5p, let-7b-5p, and their target genes during different stages of corpus luteum in Egyptian buffaloes.Journal, genetic engineering & biotechnology · 2022Article
- Comparative study of endometrial & subendometrial angiogenesis in unexplained infertile versus normal fertile women.The Indian journal of medical research · 2021Article
- Alterations in the Expression Profile of Serum miR-155, miR-223, miR-17, miR-200a, miR-205, as well as Levels of Interleukin 6, and Prostaglandins during Endometritis in Arabian Mares.Veterinary sciences · 2021Article
- Circulating miRNA 27a and miRNA150-5p; a noninvasive approach to endometrial carcinoma.Molecular biology reports · 2021Article
- MicroRNA-Mediated Gene Regulatory Mechanisms in Mammalian Female Reproductive Health.International journal of molecular sciences · 2021Review
- Endometrial microRNAs and their aberrant expression patterns.Medical molecular morphology · 2020Review
- Article
- Association between microRNA machinery gene polymorphisms and recurrent implantation failure.Experimental and therapeutic medicine · 2020Article
- MicroRNAome: Potential and Veritable Immunomolecular Therapeutic and Diagnostic Baseline for Lingering Bovine Endometritis.Frontiers in veterinary science · 2020Review
- Apoptotic functions of microRNAs in pathogenesis, diagnosis, and treatment of endometriosis.Cell & bioscience · 2020Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
During the menstrual cycle, human endometrium undergoes extensive cyclic morphologic and biochemical modifications in preparation for embryo implantation. These processes are highly regulated by ovarian steroids and various locally expressed gene products and involve inflammatory reaction, apoptosis, cell proliferation, angiogenesis, differentiation (tissue formation), and tissue remodeling. MicroRNAs (miRNAs) have emerged as key regulators of gene expression, and their altered and/or aberrant expression has been associated with establishment and progression of various disorders, including tumorigenesis. This review highlights the endometrial expression of miRNAs and their potential regulatory functions under normal and pathologic conditions such as endometriosis, dysfunctional uterine bleeding, and endometrial cancer. Given the key regulatory function of miRNAs on gene expression stability, understanding the underlying mechanisms of how endometrial miRNAs are regulated and identifying their specific target genes and their functions might lead to the development of preventive and therapeutic strategies by regulating specific target genes associated with such reproductive disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.