ArticleBiochimie2009
DNA-binding properties of the yeast Rgt1 repressor.
Article in Biochimie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Effects of ScRgt1-Like DNA-binding transcription factor SpRgt1 (SPCC320.03) on Hexose transporters gene expression in Schizosaccharomyces pombe.Archives of microbiology · 2024Article
- Casein kinases are required for the stability of the glucose-sensing receptor Rgt2 in yeast.Scientific reports · 2022Article
- Article
- The glucose metabolite methylglyoxal inhibits expression of the glucose transporter genes by inactivating the cell surface glucose sensors Rgt2 and Snf3 in yeast.Molecular biology of the cell · 2016Article
- Enhanced production of 2,3-butanediol by engineeredBiotechnology for biofuels · 2016Article
- Glucose starvation-induced turnover of the yeast glucose transporter Hxt1.Biochimica et biophysica acta · 2014Article
- Endocytosis and vacuolar degradation of the yeast cell surface glucose sensors Rgt2 and Snf3.The Journal of biological chemistry · 2014Article
- Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae.FEMS microbiology reviews · 2014Review
- Carbon source dependent promoters in yeasts.Microbial cell factories · 2014Review
- Understanding the mechanism of glucose-induced relief of Rgt1-mediated repression in yeast.FEBS open bio · 2014Article
- The glucose signaling network in yeast.Biochimica et biophysica acta · 2013Review
- Mth1 regulates the interaction between the Rgt1 repressor and the Ssn6-Tup1 corepressor complex by modulating PKA-dependent phosphorylation of Rgt1.Molecular biology of the cell · 2013Article
- Regulations of sugar transporters: insights from yeast.Current genetics · 2013Review
- Construction of yeast strains useful for screening drugs that inhibit glucose uptake and glycolysis.Analytical biochemistry · 2013Article
- Spatial promoter recognition signatures may enhance transcription factor specificity in yeast.PloS one · 2013Article
- An internal deletion in MTH1 enables growth on glucose of pyruvate-decarboxylase negative, non-fermentative Saccharomyces cerevisiae.Microbial cell factories · 2012Article
- Functional dissection of the glucose signaling pathways that regulate the yeast glucose transporter gene (HXT) repressor Rgt1.Journal of cellular biochemistry · 2011Article
- Glucose signaling-mediated coordination of cell growth and cell cycle in Saccharomyces cerevisiae.Sensors (Basel, Switzerland) · 2010Review
- Asymmetric signal transduction through paralogs that comprise a genetic switch for sugar sensing in Saccharomyces cerevisiae.The Journal of biological chemistry · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The yeast HXT (glucose transporter gene) repressor Rgt1 lacks a dimerization domain and thus appears to bind as a monomer to its consensus binding site sequence (5'-CGGANNA-3'). The HXT1 promoter contains 8 Rgt1-binding sites, but its expression is not effectively repressed by Rgt1. In the present study, the Rgt1-binding sites in the HXT1 promoter were analyzed to examine how Rgt1 mediates transcriptional repression. It is seen that Rgt1 binds the HXT1 promoter, but does not significantly mediate repression. When engineered to be multimerized without the intervening sequences between the Rgt1-binding sites, however, 4 or more Rgt1-binding sites were required to provide sufficient Rgt1-dependent repression. These findings suggest that the intervening sequences between the Rgt1-binding sites are important for the regulation of Rgt1 function and that Rgt1 functions efficiently only through multiple binding sites.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.