Evidence map›Paper›PMID 18948282›Full record

ArticleNucleic acids research2009

MODBASE, a database of annotated comparative protein structure models and associated resources.

Ursula Pieper, Narayanan Eswar, Ben M Webb, David Eramian, Libusha Kelly, David T Barkan, Hannah Carter, Parminder Mankoo, Rachel Karchin, Marc A Marti-Renom and 2 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Anticipating innovations in structural biology.Quarterly reviews of biophysics · 2018
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Computational methods in drug discovery.Pharmacological reviews · 2014
    Review
  15. Article
  16. Article
  17. Article
  18. Evolution of modular intraflagellar transport from a coatomer-like progenitor.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  19. Article
  20. PIBiophysical reviews · 2013
    Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ursula PieperDepartment of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158, USA.
Narayanan Eswar
Ben M Webb
David Eramian
Libusha Kelly
David T Barkan
Hannah Carter
Parminder Mankoo
Rachel Karchin
Marc A Marti-Renom
Fred P Davis
Andrej Sali

Funding

SUBPROJECT 5U54GM074945 · NIGMS · SGX PHARMACEUTICALS, INC. · PI BURLEY, STEPHEN KEVIN · 2005 to 2009
$46.2M
PHARMACOGENETICS OF MEMBRANE TRANSPORTERSU01GM061390 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GIACOMINI, KATHLEEN M · 2000 to 2009
$29.2M
SPECIALIZED CENTER FOR THE PROTEIN STRUCTURE INITIATIVEU54GM074929 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REIK, ROLAND · 2005 to 2009
$16.6M
Theoretical and Computational ApproachesP01GM071790 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI RAUSHEL, FRANK M. · 2004 to 2013
$15.5M
STRUCTURAL BIOLOGY TRAINING PROGRAMT32GM008284 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KORTEMME, TANJA · 1988 to 2022
$10.1M
Protein Modeling by Satisfaction of Spatial RestraintsR01GM054762 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SALI, ANDREJ · 2001 to 2008
$2.1M
NIGMS NIH HHS GM08284NIGMS NIH HHS P01 GM071790NIGMS NIH HHS P01 GM71790NIGMS NIH HHS R01 GM054762NIGMS NIH HHS R01 GM54762NIGMS NIH HHS T32 GM008284NIGMS NIH HHS U01 GM061390NIGMS NIH HHS U01 GM61390NIGMS NIH HHS U54 GM074929NIGMS NIH HHS U54 GM074945
6 · The paper itself

Abstract

MODBASE (http://salilab.org/modbase) is a database of annotated comparative protein structure models. The models are calculated by MODPIPE, an automated modeling pipeline that relies primarily on MODELLER for fold assignment, sequence-structure alignment, model building and model assessment (http:/salilab.org/modeller). MODBASE currently contains 5,152,695 reliable models for domains in 1,593,209 unique protein sequences; only models based on statistically significant alignments and/or models assessed to have the correct fold are included. MODBASE also allows users to calculate comparative models on demand, through an interface to the MODWEB modeling server (http://salilab.org/modweb). Other resources integrated with MODBASE include databases of multiple protein structure alignments (DBAli), structurally defined ligand binding sites (LIGBASE), predicted ligand binding sites (AnnoLyze), structurally defined binary domain interfaces (PIBASE) and annotated single nucleotide polymorphisms and somatic mutations found in human proteins (LS-SNP, LS-Mut). MODBASE models are also available through the Protein Model Portal (http://www.proteinmodelportal.org/).

Indexed as

Databases, ProteinModels, MolecularProtein Structure, TertiaryStructural Homology, ProteinGenomicsHumansLigandsMutationPolymorphism, Single NucleotideProtein FoldingProtein Interaction Domains and MotifsProteinsUser-Computer InterfaceLigandsProteins

Identifiers

PMID18948282
PMCPMC2686492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.