Evidence map›Paper›PMID 18947172›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2008

Whole-body plethysmography in African green monkeys (Chlorocebus aethiops) with and without jackets.

Chad D Foster, Ty C Hunter, Paul H Gibbs, Elizabeth K Leffel

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. Article
  5. Evaluation of the use of primate undershirts as a refinement practice for jacketed rhesus macaques (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2014
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chad D FosterVeterinary Medicine Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA. chad.foster1@us.army.mil
Ty C Hunter
Paul H Gibbs
Elizabeth K Leffel
United States Army Medical Research Institute of Infectious Diseases · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indwelling central venous catheters are often used to facilitate frequent phlebotomy while minimizing stress and anesthetic effects on animals. However, nonhuman primates with central venous catheters must wear protective jackets. Jackets routinely are removed for aerosol exposure to agents and respiratory measurements by whole-body plethysmography (WBP) because of the potentially confounding effects of jackets on these procedures. However, removing the jacket may dislodge the catheter, making it unusable. Using each animal as its own control, we tested 12 African green monkeys to determine whether minute volume, tidal volume, respiratory rate, or accumulated volume measurements by WBP differed depending on whether the animal wore a protective jacket or not. We found no statistical differences in any measured respiratory parameter and concluded that the jackets could be left in place on the animal while undergoing plethysmography without compromising the calculations for determining the inhaled dose of aerosolized agent. In addition, this study revealed no obvious contraindications to leaving the jacket in place in other nonhuman primate species, provided that the jacket fits appropriately and that plethysmography is performed correctly.

Indexed as

AnimalsChlorocebus aethiopsFemaleMalePlethysmography, Whole Body

Identifiers

PMID18947172
PMCPMC2691545
OpenAlexW1225437221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.