Evidence map›Paper›PMID 18946066›Full record

ReviewThe New England journal of medicine2008

Uric acid and cardiovascular risk.

Daniel I Feig, Duk-Hee Kang, Richard J Johnson

Erratum issued 3 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The New England journal of medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 1,080 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,080citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02797028 phase4unknown statusnot on this mapstarted 2015, after this paper: background citation

Investigation of the Atherogenic Effects of Uric Acid-modified in Endothelial Dysfunction and the the Preventional Mechanism by Anthocyanidines

TypeinterventionalSponsorGuangzhou General Hospital of Guangzhou Military CommandRan2015 to 2017Enrolled320ConditionsCardiovascular DiseaseArmsAnthocyanidins capsule, Placebo capsule, Allopurinol
NCT03157960 nacompletednot on this mapstarted 2012, after this paper: background citation

The Effect of Acute Fructose Load in Patients With Chronic Kidney Disease and Patients With Type 2 Diabetes Compared to Healthy Subjects

TypeinterventionalSponsorKarolinska University HospitalRan2012 to 2021Enrolled20ConditionsChronic Kidney Diseases, Diabetes Mellitus, Type 2ArmsBlueberry drink, Blueberry and pizza, Soft beverage, Soft beverage and pizza, Fructose
NCT04012294 phase3unknown statusnot on this mapstarted 2019, after this paper: background citation

Effects of Allopurinol on Inflammatory Markers and Morphostructural Changes Evidenced by Musculoskeletal Ultrasound in Individuals With Asymptomatic Hyperuricemia. A Proof of Concept

TypeinterventionalSponsorInstituto Nacional de Cardiologia Ignacio ChavezRan2019 to 2021Enrolled200ConditionsMusculoskeletal Degeneration, Inflammation, HyperuricemiaArmsAllopurinol Pill
3 · Its place in the literature

Who cites it

1,080 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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1,020 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Daniel I FeigBaylor College of Medicine, Houston, TX 77030, USA. dfeig@bcm.tmc.edu
Duk-Hee Kang
Richard J Johnson

Funding

Role of Uric Acid in Hypertension and Renal DiseaseR01HL068607 · NHLBI · UNIVERSITY OF FLORIDA · PI JOHNSON, RICHARD JOSEPH · 2002 to 2011
$3.5M
GLOMERULAR ENDOTHELIAL CELL &HEMOLYTIC UREMIC SYNDROMER01DK052121 · NIDDK · UNIVERSITY OF WASHINGTON · PI JOHNSON, RICHARD JOSEPH · 1996 to 2009
$3.3M
Uric Acid in Childhood HypertensionK23DK064587 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI FEIG, DANIEL I · 2003 to 2007
$701k
NHLBI NIH HHS HL-68607NHLBI NIH HHS R01 HL068607NIDDK NIH HHS DK064587NIDDK NIH HHS DK-52121NIDDK NIH HHS K23 DK064587NIDDK NIH HHS R01 DK052121
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesHumansHypertensionHyperuricemiaKidney DiseasesMetabolic SyndromeRisk FactorsUric AcidUric Acid

Identifiers

PMID18946066
PMCPMC2684330

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.