Evidence map›Paper›PMID 18945703›Full record

ArticleNucleic acids research2009

UCbase & miRfunc: a database of ultraconserved sequences and microRNA function.

Cristian Taccioli, Enrica Fabbri, Rosa Visone, Stefano Volinia, George A Calin, Louise Y Fong, Roberto Gambari, Arianna Bottoni, Mario Acunzo, John Hagan and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

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  6. UCbase 2.0: ultraconserved sequences database (2014 update).Database : the journal of biological databases and curation · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Cristian TaccioliDepartment of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH 43210, USA.
Enrica Fabbri
Rosa Visone
Stefano Volinia
George A Calin
Louise Y Fong
Roberto Gambari
Arianna Bottoni
Mario Acunzo
John Hagan
Marilena V Iorio
Claudia Piovan
Giulia Romano
Carlo Maria Croce
The Ohio State University · USUniversity of Ferrara · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four hundred and eighty-one ultraconserved sequences (UCRs) longer than 200 bases were discovered in the genomes of human, mouse and rat. These are DNA sequences showing 100% identity among the three species. UCRs are frequently located at genomic regions involved in cancer, differentially expressed in human leukemias and carcinomas and in some instances regulated by microRNAs (miRNAs). Here we present UCbase & miRfunc, the first database which provides ultraconserved sequences data and shows miRNA function. Also, it links UCRs and miRNAs with the related human disorders and genomic properties. The current release contains over 2000 sequences from three species (human, mouse and rat). As a web application, UCbase & miRfunc is platform independent and it is accessible at http://microrna.osu.edu/.UCbase4.

Indexed as

Conserved SequenceDatabases, Nucleic AcidAnimalsBase SequenceDNAHumansMiceMicroRNAsRatsUser-Computer InterfaceDNAMicroRNAs

Identifiers

PMID18945703
PMCPMC2686429
OpenAlexW1983452147

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.