ArticleNucleic acids research2009
UCbase & miRfunc: a database of ultraconserved sequences and microRNA function.
Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- Article
- The transcribed ultraconserved region uc.160+ enhances processing and A-to-I editing of the miR-376 cluster: hypermethylation improves glioma prognosis.Molecular oncology · 2022Article
- Article
- Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review).International journal of oncology · 2016Review
- Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis.Oncotarget · 2014Article
- UCbase 2.0: ultraconserved sequences database (2014 update).Database : the journal of biological databases and curation · 2014Article
- From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review).International journal of oncology · 2013Review
- Hyper conserved elements in vertebrate mRNA 3'-UTRs reveal a translational network of RNA-binding proteins controlled by HuR.Nucleic acids research · 2013Article
- The Role of miRNA in Haematological Malignancy.Bone marrow research · 2013Review
- Article
- Genetic variants within ultraconserved elements and susceptibility to right- and left-sided colorectal adenocarcinoma.Carcinogenesis · 2012Article
- Human microRNA oncogenes and tumor suppressors show significantly different biological patterns: from functions to targets.PloS one · 2010Article
- TAM: a method for enrichment and depletion analysis of a microRNA category in a list of microRNAs.BMC bioinformatics · 2010Article
- miRMaid: a unified programming interface for microRNA data resources.BMC bioinformatics · 2010Article
- TransmiR: a transcription factor-microRNA regulation database.Nucleic acids research · 2010Article
- Transcribed-Ultra Conserved Region expression is associated with outcome in high-risk neuroblastoma.BMC cancer · 2009Article
- Nucleic Acids Research annual Database Issue and the NAR online Molecular Biology Database Collection in 2009.Nucleic acids research · 2009Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Four hundred and eighty-one ultraconserved sequences (UCRs) longer than 200 bases were discovered in the genomes of human, mouse and rat. These are DNA sequences showing 100% identity among the three species. UCRs are frequently located at genomic regions involved in cancer, differentially expressed in human leukemias and carcinomas and in some instances regulated by microRNAs (miRNAs). Here we present UCbase & miRfunc, the first database which provides ultraconserved sequences data and shows miRNA function. Also, it links UCRs and miRNAs with the related human disorders and genomic properties. The current release contains over 2000 sequences from three species (human, mouse and rat). As a web application, UCbase & miRfunc is platform independent and it is accessible at http://microrna.osu.edu/.UCbase4.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.