ArticleAmerican journal of epidemiology2008
Maternal calcium intake during pregnancy and blood pressure in the offspring at age 3 years: a follow-up analysis of the Project Viva cohort.
Article in American journal of epidemiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Calcium supplementation during pregnancy and long-term offspring outcome: a systematic literature review and meta-analysis.Annals of the New York Academy of Sciences · 2022Pooled it
- Maternal Macronutrient Intake and Offspring Blood Pressure 20 Years Later.Journal of the American Heart Association · 2017Article
- Components of height and blood pressure in childhood.International journal of epidemiology · 2014Article
- Calcium revisited: part II calcium supplements and their effects.BoneKEy reports · 2014Review
- Article
- Metabolic syndrome: role of maternal undernutrition and fetal programming.Reviews in endocrine & metabolic disorders · 2013Review
- Early influences on cardiovascular and renal development.European journal of epidemiology · 2010Review
- Effect of maternal calcium supplementation on offspring blood pressure in 5- to 10-y-old rural Gambian children.The American journal of clinical nutrition · 2010Article
- Clinical research directions in pediatric cardiology.Current opinion in pediatrics · 2009Review
- Fetal nutritional origins of adult diseases: challenges for epidemiological research.European journal of epidemiology · 2008Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
A previous analysis of the Project Viva cohort (eastern Massachusetts, 1999-2002 recruitment) found an association between higher second-trimester supplemental maternal calcium intake and lower systolic blood pressure in offspring at 6 months. The authors analyzed 5,527 systolic blood pressure measurements from 1,173 mother-child pairs from this same cohort when the children were aged 3 years. They estimated the change in offspring blood pressure for a 500-mg difference in maternal total, dietary-only, and supplemental-only calcium intake during the first 2 trimesters of pregnancy. Mean daily total calcium intake was 1,311 mg (standard deviation, 421) in the first trimester and 1,440 mg (standard deviation, 386) in the second trimester. Mean systolic blood pressure of the offspring at age 3 years was 92.1 mm Hg (standard deviation, 10.3). None of the maternal calcium intake measures during the first and second trimesters was associated with systolic blood pressure in the offspring. For example, for each 500-mg increment in maternal total elemental calcium intake in the second trimester, child's 3-year systolic blood pressure was 0.1 mm Hg lower (95% confidence interval: -0.9, 0.6). Maternal calcium intake during pregnancy was not associated with offspring blood pressure at the age of 3 years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.