Evidence map›Paper›PMID 18945394›Full record

ArticleCurrent infectious disease reports2008

Strategies for promoting adherence to antiretroviral therapy: a review of the literature.

Jane M Simoni, K Rivet Amico, Cynthia R Pearson, Robert Malow

Abstract read
In one paragraph

Article in Current infectious disease reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Alcohol use and antiretroviral adherence: review and meta-analysis.Journal of acquired immune deficiency syndromes (1999) · 2009
    Pooled it
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  9. Cognitive behavioral therapy for body image and self-care (CBT-BISC) in sexual minority men living with HIV: A randomized controlled trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2017
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  13. Pilot RCT of bidirectional text messaging for ART adherence among nonurban substance users with HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2015
    Trial
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56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jane M SimoniDepartment of Psychology, University of Washington, Campus Box 351525, Seattle, WA 98195, USA. jsimoni@u.washington.edu
K Rivet Amico
Cynthia R Pearson
Robert Malow

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
PEER SUPPORT TO ENHANCE ANTIRETROVIRAL ADHERENCER01MH058986 · NIMH · YESHIVA UNIVERSITY · PI SIMONI, JANE MARIE · 1999 to 2006
$2.8M
Addressing Depression and ART Adherence in HIV+ Adults on the US-Mexico BorderR34MH084674 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2008 to 2010
$769k
NIAID NIH HHS P30 AI027757NIMH NIH HHS R01 MH058986NIMH NIH HHS R34 MH084674
6 · The paper itself

Abstract

The success of antiretroviral therapy (ART) for HIV infection, though widespread and resounding, has been limited by inadequate adherence to its unforgiving regimens, especially over the long term. This article summarizes the literature on behavioral interventions to promote ART adherence and highlights some of the most recent and innovative research on patient education and case management, modified directly observed therapy, contingency management, interventions emphasizing social support, and novel technologies to promote awareness. Research in the area of adherence in pediatric HIV infection and in resource-constrained international settings also is considered. Although adherence interventions have been successful in experimental trials, they may not be feasible or adaptable given the constraints of real-world clinics and community-based settings. Implementation and dissemination of adherence interventions needs increased attention as ART adherence research moves beyond its first decade. We conclude with suggestions for incorporating research findings into clinical practice.

Identifiers

PMID18945394
PMCPMC4059830

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.