Evidence map›Paper›PMID 18941777›Full record

ArticleEuropean journal of pediatrics2009

Policies and practices for the clinical management of HIV/HCV coinfected children in Europe: an epidemiological survey.

Kirsty England, Claire Thorne, Lucy Pembrey, Marie-Louise Newell

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Kirsty EnglandMRC Centre of Epidemiology for Child Health, Institute of Child Health, University College London, London, UK. k.england@ich.ucl.ac.uk
Claire Thorne
Lucy Pembrey
Marie-Louise Newell
University College London · GBUCL Australia · AU

Funding

Department of HealthMedical Research Council G0400546Wellcome Trust 081082
6 · The paper itself

Abstract

The antenatal prevalence of HIV/HCV coinfection ranges from 12% to 28% with mother-to-child transmission rates ranging from 3.6% to 9.5%. There are no guidelines detailing the most appropriate clinical management and treatment of coinfected children. We used a semi-structured questionnaire to investigate current European practices for the management and follow-up of HIV/HCV coinfected children among clinical centres contributing to the European Collaborative Study or the European Paediatric HCV Network. Clinicians from 16 out of 24 clinical centres responded and were caring for a total of 44 HIV/HCV coinfected children. We found that, although there was a high level of concordance regarding testing for HIV and/or HCV infection, monitoring practices in these European centres varied widely. Few clinicians stated they would administer HIV and HCV treatment concurrently. Limited experience in the clinical management of this group and the lack of an evidence base to guide policy may be a barrier to achieving optimal care and treatment.

Indexed as

Practice Guidelines as TopicPractice Patterns, Physicians'AdolescentAdultAnti-HIV AgentsAntiviral AgentsChildChild, PreschoolComorbidityDrug MonitoringDrug Therapy, CombinationEuropeHealth Care SurveysHepatitis CHIV InfectionsHumansAnti-HIV AgentsAntiviral Agents

Identifiers

PMID18941777
OpenAlexW1986947129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.