ArticleInternational archives of occupational and environmental health2009
Arsenic levels in ground water and cancer incidence in Idaho: an ecologic study.
Article in International archives of occupational and environmental health, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Carcinogenic effect of arsenic in digestive cancers: a systematic review.Environmental health : a global access science source · 2023Pooled it
- Drinking water and the implications for gender equity and empowerment: A systematic review of qualitative and quantitative evidence.International journal of hygiene and environmental health · 2023Pooled it
- A Systematic Review and Meta-Regression Analysis of Lung Cancer Risk and Inorganic Arsenic in Drinking Water.International journal of environmental research and public health · 2015Pooled it
- Arsenic in Drinking Water and Incidences of Leukemia and Lymphoma: Implication for Its Dual Effects in Carcinogenicity.Frontiers in public health · 2022Article
- Aggregated cumulative county arsenic in drinking water and associations with bladder, colorectal, and kidney cancers, accounting for population served.Journal of exposure science & environmental epidemiology · 2021Article
- Exploratory study of the association in the United Kingdom between hypertension and inorganic arsenic (iAs) intake from rice and rice products.Environmental geochemistry and health · 2021Article
- Health effects among a cohort exposed to low-level arsenic in a geothermal area of Tuscany, Italy.International archives of occupational and environmental health · 2018Article
- Arsenic Exposure and Cancer Risk Reduction with Local Ordinance Requiring Whole-House Dual-Tank Water Treatment Systems.Human and ecological risk assessment : HERA · 2018Article
- Article
- Relationships between arsenic concentrations in drinking water and lung and bladder cancer incidence in U.S. counties.Journal of exposure science & environmental epidemiology · 2017Article
- Arsenic in Drinking Water and Lung Cancer Mortality in the United States: An Analysis Based on US Counties and 30 Years of Observation (1950-1979).Journal of environmental and public health · 2016Article
- Age adjustment in ecological studies: using a study on arsenic ingestion and bladder cancer as an example.BMC public health · 2011Article
- Utility of recent studies to assess the National Research Council 2001 estimates of cancer risk from ingested arsenic.Environmental health perspectives · 2011Review
- Lung cancer in a U.S. population with low to moderate arsenic exposure.Environmental health perspectives · 2009Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLong-term exposure to arsenic above 50 microg/L in drinking water has been related to multiple types of cancers. Few epidemiologic studies conducted in the US have detected an association between regional exposures below this level in drinking water and corresponding cancer occurrence rates. This county-level ecologic study evaluates arsenic levels in ground water and its association with targeted cancer incidence in Idaho, where some regions have been found to contain higher arsenic levels.
methodsUsing cancer incidence data (1991-2005) from the Cancer Data Registry of Idaho and arsenic data (1991-2005) from the Idaho Department of Environmental Quality, we calculated the age-adjusted incidence rate for cancers of the urinary bladder, kidney and renal pelvis, liver and bile duct, lung and bronchus, non-Hodgkin's lymphoma (NHL), and all malignant cancers according to arsenic levels in ground water. Multivariate regression analysis was applied to evaluate the relationship between arsenic levels in ground water and cancer incidence.
resultsFor males, but not for females, age-adjusted incidence for lung cancer and all malignant cancers was significantly higher in the intermediate arsenic counties (2-9 microg/L, n = 16) and the high arsenic counties (>or=10 microg/L, n = 5) compared to the low arsenic counties (<2.0 microg/L, n = 23). When adjusted for race, gender, population density, smoking and body mass index (BMI), no relationship was found between arsenic levels in ground water and cancer incidence.
conclusionsIn this ecological design, exposure to low-level arsenic in ground water is not associated with cancer incidence when adjusting for salient variables. For populations residing in southwestern Idaho, where arsenic has been found to exceed 10 microg/L in ground water, individual risk assessment is required in order to determine whether there is a link between long-term arsenic exposure at these levels and cancer risk.
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