ReviewLab on a chip2008
Microfabricated implants for applications in therapeutic delivery, tissue engineering, and biosensing.
Review in Lab on a chip, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 115 citations in OpenAlex.
- Nanoparticle vaccine formulations for dengue virus.RSC pharmaceutics · 2026Review
- Rise of implantable drugs: A chronicle of breakthroughs in drug delivery systems.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024Review
- Advancements in Polymer Biomaterials as Scaffolds for Corneal Endothelium Tissue Engineering.Polymers · 2024Review
- Clinical and Preclinical Methods of Heat-Stabilization of Human Vaccines.Molecular pharmaceutics · 2024Review
- Micro and nanotechnologies: The little formulations that could.Bioengineering & translational medicine · 2023Review
- Microfabrication approaches for oral research and clinical dentistry.Frontiers in dental medicine · 2023Review
- Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects.Drug delivery · 2022Review
- Considerations for Size, Surface Charge, Polymer Degradation, Co-Delivery, and Manufacturability in the Development of Polymeric Particle Vaccines for Infectious Diseases.Advanced nanobiomed research · 2021Article
- Catecholamine-Copper Redox as a Basis for Site-Specific Single-Step Functionalization of Material Surfaces.ACS applied materials & interfaces · 2021Article
- Microfabrication and Surface Functionalization of Soda Lime Glass through Direct Laser Interference Patterning.Nanomaterials (Basel, Switzerland) · 2021Article
- An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components.Journal of visualized experiments : JoVE · 2018Article
- Photopolymerized micropatterns with high feature frequencies overcome chemorepulsive borders to direct neurite growth.Journal of tissue engineering and regenerative medicine · 2018Article
- Additive manufacturing of hydrogel-based materials for next-generation implantable medical devices.Science robotics · 2017Article
- Fabrication and Applications of Micro/Nanostructured Devices for Tissue Engineering.Nano-micro letters · 2017Review
- A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention.Advanced healthcare materials · 2016Article
- Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2016Review
- Micro/nanofabricated platforms for oral drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2015Review
- Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs.Advanced healthcare materials · 2014Article
- Hybrid integrated label-free chemical and biological sensors.Sensors (Basel, Switzerland) · 2014Review
- Planar bioadhesive microdevices: a new technology for oral drug delivery.Current pharmaceutical biotechnology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
By adapting microfabrication techniques originally developed in the microelectronics industry novel devices for drug delivery, tissue engineering and biosensing have been engineered for in vivo use. Implant microfabrication uses a broad range of techniques including photolithography, and micromachining to create devices with features ranging from 0.1 to hundreds of microns with high aspect ratios and precise features. Microfabrication offers device feature scale that is relevant to the tissues and cells to which they are applied, as well as offering ease of en masse fabrication, small device size, and facile incorporation of integrated circuit technology. Utilizing these methods, drug delivery applications have been developed for in vivo use through many delivery routes including intravenous, oral, and transdermal. Additionally, novel microfabricated tissue engineering approaches propose therapies for the cardiovascular, orthopedic, and ocular systems, among others. Biosensing devices have been designed to detect a variety of analytes and conditions in vivo through both enzymatic-electrochemical reactions and sensor displacement through mechanical loading. Overall, the impact of microfabricated devices has had an impact over a broad range of therapies and tissues. This review addresses many of these devices and highlights their fabrication as well as discusses materials relevant to microfabrication techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.