Evidence map›Paper›PMID 18941609›Full record

ArticleTexas Heart Institute journal2008

Cardiac surgery during pregnancy.

Anish Patel, Sanjay Asopa, Augustine T M Tang, Sunil K Ohri

Open access · greenAbstract read
In one paragraph

Article in Texas Heart Institute journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Valvular Heart Disease in Pregnancy.Methodist DeBakey cardiovascular journal · 2024
    Review
  6. Review
  7. Management of Ischemic Heart Disease in Pregnancy.Current atherosclerosis reports · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. [Surgical management of pregnancy-associated acute Stanford type A aortic dissection: analysis of 5 cases].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017
    Article
  14. Article
  15. Off Pump Coronary Artery Bypass Surgery for Multivessel Disease in Pregnancy.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2016
    Article
  16. A Historic Case of Cardiac Surgery in Pregnancy.Case reports in obstetrics and gynecology · 2016
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anish PatelWessex Cardiothoracic Centre, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom.
Sanjay Asopa
Augustine T M Tang
Sunil K Ohri
Southampton General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular adaptations during pregnancy are normally well tolerated in healthy women. However, 2% to 4% of women of childbearing age have some degree of concomitant heart disease, and these changes may compromise cardiac function. Of these, a few who do not respond to medical treatment may require surgical correction. In this setting, maternal mortality rate has improved to levels similar to those in non-pregnant counterparts. However, the fetal mortality rate remains high (up to 33%). Factors contributing to high fetal mortality rates include the timing of the operation, the urgency of the operation, and the fetal/fetoplacental response to cardiopulmonary bypass. Modulation of the fetoplacental response to cardiopulmonary bypass may prevent placental dysfunction and sustained uterine contractions, which underlie fetal hypoxia and acidosis.In this article, we review cardiovascular adaptations to pregnancy and the pathophysiologic effects of cardiopulmonary bypass on the mother, fetus, and fetoplacental unit, and we talk about whether manipulation of these responses can help in improving fetal outcome. Finally, approaches regarding perfusion management and off-pump cardiac surgical techniques in pregnancy are discussed.

Indexed as

Cardiopulmonary BypassFemaleFetal DeathHeart Defects, CongenitalHeart DiseasesHumansInfant, NewbornIntraoperative ComplicationsPlacental CirculationPostoperative ComplicationsPregnancyPregnancy Complications, CardiovascularSurvival AnalysisUnited KingdomUterine ContractionCardiac surgical procedurescardiopulmonary bypass/adverse effectsfemaleheart defects, congenitalpregnancy complications, cardiovascular/etiology/surgery

Identifiers

PMID18941609
PMCPMC2565548
OpenAlexW1539987269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.