ArticleEnvironmental health perspectives2008
Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement.
Article in Environmental health perspectives, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
107 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Outdoor air pollutants and asthma risk in adolescents: evidence from a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Traffic-Related Air Pollution and Childhood Asthma: Recent Advances and Remaining Gaps in the Exposure Assessment Methods.International journal of environmental research and public health · 2017Pooled it
- What Is the Relationship between Outdoor Time and Physical Activity, Sedentary Behaviour, and Physical Fitness in Children? A Systematic Review.International journal of environmental research and public health · 2015Pooled it
- Proximity to major roadways and asthma symptoms in the School Inner-City Asthma Study.The Journal of allergy and clinical immunology · 2020Trial
- Assessment of the capacity of vehicle cabin air inlet filters to reduce diesel exhaust-induced symptoms in human volunteers.Environmental health : a global access science source · 2014Trial
- Intersections as Hot Spots: Assessing the Contribution of Localized Nontailpipe Emissions and Noise on the Association Between Traffic and Children's Lung Function.Research report (Health Effects Institute) · 2026Article
- Ambient Air Pollution and COVID-19 in California.Research report (Health Effects Institute) · 2026Article
- Article
- The Airport, Air Quality and Asthma (AAA) Indoor Air Intervention Trial for Children with Asthma: Protocol for a Community Based Study in South King County, Washington State.Research square · 2025Article
- Article
- Reduced Childhood Ambient Fine Particulate Matter Exposure and Subsequent Asthma Incidence: How Low Is Low Enough?Annals of the American Thoracic Society · 2024Article
- Birth Cohort Studies of Long-Term Exposure to Ambient Air Pollution in Early Life and Development of Asthma in Children and Adolescents from Denmark.Research report (Health Effects Institute) · 2024Article
- Determinants of active trachoma among rural children aged 1-9 years old in Aw-Bare Wereda, Somali Region of Ethiopia: a cross-sectional study.Journal of health, population, and nutrition · 2024Article
- Prenatal and childhood air pollution exposure, cellular immune biomarkers, and brain connectivity in early adolescents.Brain, behavior, & immunity - health · 2024Article
- Early-Life Exposure to Air Pollution and Childhood Asthma Cumulative Incidence in the ECHO CREW Consortium.JAMA network open · 2024Article
- Airborne Suspended Particulate Matter and the Prevalence of Allergic Conjunctivitis in Japan.Cureus · 2024Article
- Role of Air Pollution in the Development of Asthma Among Children with a History of Bronchiolitis in Infancy.Epidemiology (Cambridge, Mass.) · 2023Article
- Social Inequities in Exposure to Traffic-Related Air and Noise Pollution at Public Schools in Texas.International journal of environmental research and public health · 2023Article
- Environmental justice and allergic disease: A Work Group Report of the AAAAI Environmental Exposure and Respiratory Health Committee and the Diversity, Equity and Inclusion Committee.The Journal of allergy and clinical immunology · 2023Article
- Evaluation of Health Economic Loss Due to Particulate Matter Pollution in the Seoul Subway, South Korea.Toxics · 2023Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
backgroundThe question of whether air pollution contributes to asthma onset remains unresolved.
objectivesIn this study, we assessed the association between asthma onset in children and traffic-related air pollution.
methodsWe selected a sample of 217 children from participants in the Southern California Children's Health Study, a prospective cohort designed to investigate associations between air pollution and respiratory health in children 10-18 years of age. Individual covariates and new asthma incidence (30 cases) were reported annually through questionnaires during 8 years of follow-up. Children had nitrogen dioxide monitors placed outside their home for 2 weeks in the summer and 2 weeks in the fall-winter season as a marker of traffic-related air pollution. We used multilevel Cox models to test the associations between asthma and air pollution.
resultsIn models controlling for confounders, incident asthma was positively associated with traffic pollution, with a hazard ratio (HR) of 1.29 [95% confidence interval (CI), 1.07-1.56] across the average within-community interquartile range of 6.2 ppb in annual residential NO2. Using the total interquartile range for all measurements of 28.9 ppb increased the HR to 3.25 (95% CI, 1.35-7.85).
conclusionsIn this cohort, markers of traffic-related air pollution were associated with the onset of asthma. The risks observed suggest that air pollution exposure contributes to new-onset asthma.
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