Evidence map›Paper›PMID 18941403›Full record

ArticleThe American journal of surgical pathology2009

Ectopic low-grade adrenocortical carcinoma in the spinal region: immunohistochemical and molecular cytogenetic study of a pediatric case.

Fausto J Rodriguez, Bernd W Scheithauer, Lori A Erickson, Robert B Jenkins, Caterina Giannini

Abstract readCase Reports
In one paragraph

Article in The American journal of surgical pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Emergence of Ectopic Adrenal Tissues-What are the Probable Mechanisms?Journal of clinical research in pediatric endocrinology · 2022
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Spinal adrenal cortical adenoma associated with Beckwith-Wiedemann syndrome: case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Review
  11. Review
  12. 24-Year-Old Woman with Recent Onset Back Pain.Brain pathology (Zurich, Switzerland) · 2015
    Article
  13. Review
  14. Functional ectopic adrenal carcinoma in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2014
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fausto J RodriguezDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA. rodriguez.fausto@mayo.edu
Bernd W Scheithauer
Lori A Erickson
Robert B Jenkins
Caterina Giannini
Mayo Clinic in Arizona · US

Funding

Research Training Program in Neuro-OncologyT32NS007494 · NINDS · MAYO CLINIC ROCHESTER · PI O'NEILL, BRIAN PATRICK · 2002 to 2014
$1.4M
NINDS NIH HHS T32 NS007494NINDS NIH HHS T32 NS07494-04
6 · The paper itself

Abstract

Ectopic adrenocortical neoplasms arising in the nervous system are very rare. We encountered an intradural, extramedullary case of an adrenocortical neoplasm of indeterminate malignant potential affecting a spinal nerve root in the distal lumbar region of a 5-month-old girl. The lesion recurred 6 months after the initial gross total resection. The tumor in both resections had increased mitotic activity (5/10 high power fields) and MIB-1 labeling indices of 23% and 33% at initial resection and recurrence, respectively. Both tumors demonstrated gains of chromosomes 5 and 12 by interphase cytogenetics, whereas insulin growth factor 2 was identified in the recurrent tumor by immunohistochemistry. This report demonstrates that ectopic adrenocortical tumors in the nervous system may exhibit clinicopathologic and cytogenetic features suggestive of adrenocortical carcinoma.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical CarcinomaFemaleHumansImmunohistochemistryInfantIn Situ Hybridization, FluorescenceMagnetic Resonance ImagingMicroscopy, Electron, TransmissionNeoplasm Recurrence, LocalSpinal Nerve Roots

Identifiers

PMID18941403
PMCPMC3427599
OpenAlexW2069279017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.