Evidence map›Paper›PMID 18936782›Full record

ReviewNature immunology2008

New developments in mast cell biology.

Janet Kalesnikoff, Stephen J Galli

Open access · greenAbstract readReview
In one paragraph

Review in Nature immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 324 papers.

0numbers the graph read from it
0cells of the map it votes in
324citing papers in PubMed
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

324 citing papers in PubMed, 740 citations in OpenAlex.

  1. A Review: Mast Cells as Targets for Glucocorticoid Action.Current allergy and asthma reports · 2026
    Review
  2. The role of myeloid immune cells in lung epithelial repair.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  3. Effects ofMolecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Platelet-mast cell dialogue in innate immune response and inflammation.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Mastocytosis.Nature reviews. Disease primers · 2025
    Review
  13. Dissecting SNARE-Mediated Exocytosis in RBL-2H3 Mast Cells.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

264 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Janet KalesnikoffDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA. jkalesni@stanford.edu
Stephen J Galli
Stanford University · US

Funding

Role of Mast Cells in Inflammation and ImmunityR01CA072074 · NCI · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 1996 to 2010
$4.4M
Expression and Modulation of Mast Cell Function in AsthmaR01AI070813 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2006 to 2010
$2.5M
Regulation of Mast Cell Development and FunctionR01AI023990 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 1986 to 2010
$2.4M
NCI NIH HHS R01 CA072074NIAID NIH HHS R01 AI023990NIAID NIH HHS R01 AI070813
6 · The paper itself

Abstract

Mast cells can function as effector and immunoregulatory cells in immunoglobulin E-associated allergic disorders, as well as in certain innate and adaptive immune responses. This review focuses on exciting new developments in the field of mast cell biology published in the past year. We highlight advances in the understanding of FcvarepsilonRI-mediated signaling and mast cell-activation events, as well as in the use of genetic models to study mast cell function in vivo. Finally, we discuss newly identified functions for mast cells or individual mast cell products, such as proteases and interleukin 10, in host defense, cardiovascular disease and tumor biology and in settings in which mast cells have anti-inflammatory or immunosuppressive functions.

Indexed as

AnimalsAntigen PresentationCardiovascular DiseasesHumansHypersensitivity, ImmediateImmune ToleranceInflammation MediatorsInterleukin-10Mast CellsMiceNeoplasmsPeptide HydrolasesReceptors, IgESignal TransductionInflammation MediatorsInterleukin-10Peptide HydrolasesReceptors, IgE

Identifiers

PMID18936782
PMCPMC2856637
OpenAlexW1972447401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.