Evidence map›Paper›PMID 18935966›Full record

ReviewSeminars in cell & developmental biology2009

ADAM function in embryogenesis.

Dominique Alfandari, Catherine McCusker, Hélène Cousin

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Micro-Engineered Models of Development Using Induced Pluripotent Stem Cells.Frontiers in bioengineering and biotechnology · 2019
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. miR-126 inhibits cell growth, invasion, and migration of osteosarcoma cells by downregulating ADAM-9.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dominique AlfandariDepartment of Veterinary and Animal Sciences, University of Massachusetts Amherst, Paige lab. Rm. 203, 161 Holdsworth Way, Amherst, MA 01003, United States. alfandar@vasci.umass.edu
Catherine McCusker
Hélène Cousin
University of Massachusetts Amherst · US

Funding

Mechanism of Xenopus Cranial Neural Crest Cell MigrationR01DE016289 · NIDCR · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ALFANDARI, DOMINIQUE R · 2006 to 2022
$5.4M
NIDCR NIH HHS DE016289NIDCR NIH HHS R01 DE016289
6 · The paper itself

Abstract

Cleavage of proteins inserted into the plasma membrane (shedding) is an essential process controlling many biological functions including cell signaling, cell adhesion and migration as well as proliferation and differentiation. ADAM surface metalloproteases have been shown to play an essential role in these processes. Gene inactivation during embryonic development have provided evidence of the central role of ADAM proteins in nematodes, flies, frogs, birds and mammals. The relative contribution of four subfamilies of ADAM proteins to developmental processes is the focus of this review.

Indexed as

Embryonic DevelopmentADAM ProteinsAnimalsCell MovementCell ProliferationHumansModels, BiologicalADAM Proteins

Identifiers

PMID18935966
PMCPMC2693894
OpenAlexW2024424639

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.