Evidence map›Paper›PMID 18931937›Full record

ArticleMycopathologia2009

Clinical characteristics and outcomes in patients with pulmonary blastomycosis.

Doug Kralt, Bruce Light, Mary Cheang, Tracy MacNair, Lyle Wiebe, Bill Limerick, Pete Sarsfield, Greg Hammond, Kerry MacDonald, Elly Trepman and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Article
  3. AFrontiers in fungal biology · 2026
    Article
  4. Article
  5. Article
  6. Osteoarticular Mycoses.Clinical microbiology reviews · 2022
    Review
  7. Article
  8. Disseminated blastomycosis causing scapular destruction.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. A large community outbreak of blastomycosis in Wisconsin with geographic and ethnic clustering.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Article
  16. Article
  17. Article
  18. Computed tomographic scan evaluation of pulmonary blastomycosis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2009
    Article
  19. Review
  20. Blastomycosis in northwestern Ontario, 2004 to 2014.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Doug KraltFaculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Bruce Light
Mary Cheang
Tracy MacNair
Lyle Wiebe
Bill Limerick
Pete Sarsfield
Greg Hammond
Kerry MacDonald
Elly Trepman
John M Embil
University of Manitoba · CALake District Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlastomycosis is an uncommon granulomatous infection caused by the thermally dimorphic fungus Blastomyces dermatitidis. The most frequent clinical infections involve the lung, skin, and bone. Pulmonary manifestations range from asymptomatic self-limited infection to severe diffuse pneumonia causing respiratory failure.

objectivesTo establish the clinical characteristics and outcomes of patients with pulmonary blastomycosis diagnosed at hospitals in Manitoba and northwestern Ontario, Canada.

methodsA retrospective review of medical records was done for 318 patients with blastomycosis in these regions.

resultsThe majority of patients were Caucasian (198 (62.5%) patients), male (193 (61%) patients), and residents of Ontario (209 (65.7%) patients). Most patients were treated in an inpatient hospital ward (266 (84%) patients) and survived (294 (92%) patients). Pulmonary involvement, either alone or associated with other sites, was present in 296 (93%) of the 318 patients; 22 (7%) patients had no evidence of pulmonary blastomycosis. The majority of patients had localized lung disease (1-3 quadrants on chest radiograph involved; 225 (82%) patients). Of 294 (92%) patients requiring hospitalization, 266 (90%) patients received all inpatient care on a general medical ward; 28 (10%) patients received some care in the intensive care unit (ICU). Factors associated with ICU admission included diffuse pulmonary disease (four quadrants involved on chest radiograph), diabetes, and prior use of antimicrobial therapy. Twenty-four (8%) patients died, and multivariate analysis showed that older age and Aboriginal ethnicity were the significant risk factors for death from blastomycosis.

conclusionBlastomycosis is a cause of serious, potentially life-threatening pulmonary infection in this geographic region.

Indexed as

Age FactorsAnti-Bacterial AgentsBlastomycosisFemaleHumansIntensive Care UnitsLung Diseases, FungalMaleMedical RecordsOntarioRetrospective StudiesRisk FactorsTreatment OutcomeAnti-Bacterial Agents

Identifiers

PMID18931937
OpenAlexW1997627643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.